Golovna - Ailment heart i sudin
Antiviral drugs for herpes injections. Effective injections against the herpes virus. Basic mechanisms of anti-tine drugs

Against the risk of being more often recognized as a drug when you are quiet and vicious in home practice for independent treatment people. Well, for the drugs, how much smell is effective and not good, why is it worth it? Can you still turn more beautifully to the traditional folk anti-tiery zasobiv - tsibuli, milk with honey? And it has long been effective for them to enjoy the "cold", infectious and viral ailments, why should they be guided by the decrease? Proceedings and comments in our statute.

Anti-infectious drugs in the vicinity of the group. It is done through those antibacterial drugs that do not need to be added to the development of viruses. Such a lack of interest in the virus is tied to the little ones and the peculiarities of Budova. For the sake of triviality, we will try to install, say, the size of our planet and an apple. So the axis, the planet in our application is the middle size of the microbe, and the apple for us is the virus.

Viruses are stocked nucleic acids- Dzherel self-production information and drink capsules. In the body of the "ruler" there can be more proliferation behind the friendly minds, including for the additional "information" in the cell of the sick body, as they themselves repair the formation of pathogens. It is the responsibility of the people (blood cells) that is most often powerless in front of them. The number of known ailments viruses is more than 500.

The first drug, with volodya anti-tiering powers, having been removed in the distant 1946, was named Thiosemicarbazone. Yak mainly to become, when entering the warehouse of Faringosept, clinical medicine to fight z fired up throat. Then they got rid of the idoxuridin to get stuck against the virus.

Brutal respect:a breakthrough in the virology of the knowledge of human interferon - bilka, the vital life of viruses.

Since the ear of the 80s of the last century, there have been active robots in the development of drugs, which stimulate the synthesis of interferon by organisms.

Science robots are trivial in our hour. Sorry, parti anti-tier drugs finish the temple.

It's a pity, but on the pharmaceutical market in our days there was a great number of podboks - drugs, but not by volody, or by stimulating authorities, according to the essence of "placebo - empty".

See anti-tier drugs

All anti-tartar preparations can be divided into 2 groups:

  1. immunostimulants- likas, zdatnі short-hour rank of rapidly growing interferons.
  2. opposing- medications, given a direct injection into the virus and blocking of the multiplication.
Recommended reading:

According to the diy on the rise, the viruses are on the vid:

  • anti-layer drugs, which are used to inflate;
  • medications, straightened against the herpes virus;
  • how to adjust the activity of retroviruses;

Beast to respect: Okremo can see a group of drugs that are intended for treatment (virus in immunodeficiency).

Effective anti-tartar remedy against influenza є amantadine... Amantadine is an inexpensive and effective anti-tier. Win in small doses of zdatnyy induce reproduction of influenza virus type A at the earliest stage.

Amantadine blocking the necessary speech through the membrane of the virus and overwhelming the cytoplasm of the patient's cell. The same preparation will destroy the normal process of development of a new synthesized virus. It's a pity, ale at trivial stasis up to the whole lykarsky way, you can formulate the strength of viruses in influenza.

Similar to Volodya's antihypertensive drugs - Remantadin (Remantadin).

An offense to a number of non-business (side) effects.

On the other hand, you can win:

  • problems of the bowel and intestines - with vomiting, and impaired appetite;
  • pestilence and nervous sleep, loss of concentration and respect;
  • great doses can be felt of the appearance of changes in evidence, court attacks, illusory appearances right up to hallucinations;

importantly: safety is required when receiving vaginites. Children can be recognized not earlier than the World War II.

The most important statistics, prophylactic use of the drug during the period of influenza A allows you to detect the development of ailments in 70-90% of cases of infection.

With a rosy influenza, amantadine is consumed, or Rimantadin will soon become sick, and we will fall short and change the period of seeing a virus.

Protigrypozne with Arbidol

Arbidol is another drug that can be used to reduce anti-tier conditions, and can become stagnant against the flu. . Volodya is a direct infusion on the stifling of reproductive vitality to the virus, and on the activation of immune systems, the body, the growth of T-lymphocytes and macrophages, who are already fighting against the flu. In addition, Arbidol increases the activity and number of NK-clitins, specific "kelers" viruses. Krim tsikh of power, є is an antioxidant. I can take a prophylactic action for penetrating yak in infected cells, as well as in health. Volodya is bigger with a wide counter-tier. The range of this disease also includes influenza viruses B, C, as well as bird flu viruses.

importantly:anti-tiering drug can be powerful for allergen, but it is a manifestation of a side effect. Recommended yak anti-tier for children from 3 years.

Priyom tsikh lіkіv nadaє positive injectionі in case of accelerated influenza, GDVI, viral hike, etc.

Peculiarities of anti-tier anti-tiering Oseltamivir

in the organisms of ailing people, it transforms into an active carboxylate, which is volodymy (inhibitory) on the enzyme of viruses in influenza A, B.

Head yogo specialty polyagaє in that, wіn dіє on shtami, stiyki to amantadine. At the same time, Oseltamiviru viruses consume the health of active expansion. The number of persistent to new viruses in influenza A is slightly lower than in the previous drugs. Most effective against viruses in influenza B. Vivoditsya nirkami of indifference.

Acceptance of the antihypertensive drug can be supravodzhuvatisya by the dislocation of the shlunkovo-intestinal tract, which significantly change, as the drug is taken for an hour. Recommended for all types of categories. In addition, it is stored in warehouses for anti-tier supplies for children. Oseltamivir in the period of influenza significantly reduces the possibility of obtaining bacterial acceleration - by about 40-50%.

Brutal respect:The preparations are displayed with effective anti-layer methods from the cold.

Medicinal preparations, which are antihyperpetic authorities

Naybilsh with extensions є 1 type of herpes virus, which manifests itself on the skin, mucous membrane of the mouth, in the stravohode, in the membranes of the brain.

The 2nd type of vicious pathological problems is most often in the area of ​​statutory organs, sidnitsy and rectum.

The most effective drug of the group of groups buv vidarabin, otrimaniy in 1977 rotsi. However, the order of the effectiveness of the winners is serious by the sidelines and contraindications. To that, the bulo was primed only in two important drops and was life shows.

Acyclovir has appeared on the ear of the 80s. The main activity of the polyagent preparation is in driving the synthesis of DNA viruses in a pathway into the pathological DNA of acyclovirthophosphate, which is responsible for the growth of a virus. Let's pick the rank of din and valacyclovir . However, herpes viruses often develop stiffness up to the number of times.

Acyclovir, with internal consumption of good, penetrates into the tissues of the body. The portability of liquor is good, but it can be less likely to break down the intestines with,. inodi to appear head b_l, Destruction of svidomostі. Describes the development of nirkovo deficiency.

It’s stagnant in the middle, so it’s called in viglyadi ointments.

The rate of infection in herpes is increasing rapidly when the family suffers from famciclovir and penciclovir infection. Mechanism injected on viruses in cich drugs similar to that in Acyclovir. Vicious efficacy is the same as in Acyclovir.

Ganciclovir is also an analogous acyclovir for a day. Freeze for the treatment of all types of herpes virus.

Brutal respect:Ganciclovir is a specific drug for the elimination of cytomegalovirus.

gravely: when the drug is consumed, it is necessary to monitor the blood analysis, so as lykarskiy zasib Generally, the blood-loving function and the central policy of the central nervous system... Zastosuvannya during vaginosti is hardened through the ear of the ear into the pond.

With oper_zuyuchy deprivation of indications Valacyclovir.

Mechanism of the anti-Russian action of adoxuridin is in the phase of vivchennya. Tsey drug zasosovuyut mussevo for the treatment of herpetic visipans. Ale vin, in addition to the anti-virus efficiency, yes, part of the secondary efficiency in the viglyad most of the views, Sverbіnnya and nabryaku.

Interferon group preparations

Recommended reading:

Interferon - a chain of cells, which are seen as cells of the body, attack by viruses. The main thing is the transfer of information about the need for activation of local authorities to the organisms for the introduction of pathological organisms.

Before anti-tier drugs in the whole group, include:

  • anti-tiering zasib, how to let a candle and ointments go to the viglyad, zastosovuyutsya since 1996 rock. Scientific proofs and clinical vip tests without passing through, but in practical medicine showing yourself a yak effective drug in lіkuvannі herpetic visipans in adults and children.

Brutal respect: contraindications for vaginal and women who are breastfeeding. Doslіdzhennya on yogo dії trivayut. Volodya is a very good man.

Robots for a joke of new inexpensive anti-tiering devices cannot be pushed. Positive successes in the whole process indicate the need to develop directly pharmacology and distance.

At the end of the war, it means that the group of anti-tier workers was previously in the stage of retail outlets, far from all the food that was assigned to the doctors. Do not be clear about the mechanism of the process, the effectiveness and the side effects of the already obvious drugs, try to show the new ones effective ways fight against viruses.

stuck in for all sick people, It is important not to go into self-indulgence. It is necessary to vikoristovuvati preparations with a confirmed efficiency and do not inject, if only for the recommendation of a doctor.

Brutal respect: especially take care of the little kids' needs. Do not be hungry for an anti-Russian drug for the baby.

About the special features of the appointment and consumption of anti-tartar preparations for children in the video-survey of the doctor Komarovskiy:

Oleksandr Lotini, doctor-radiologist

Injections from herpes are required only in cases of great or often recurrent infections. You should insist on such a camp when there is a sickness in the hospital stage, or to reach a lowered immunity, an unhealthy rhythm of life, transplantation of the cystic brain or other viruses (for example, VIL).

In the course of taking antihyperpetic drugs after being carried out according to the doctor's indications, she had a second history of the patient. Vibir of medicines to be primed on the camp of the sick and their individual specialties. Stagnation of such serious problems without consulting a doctor can mean ruining the camp.

Elimination of herpes with injections can be anti-weed, immunomodulatory or combined. Adequate therapy is to add a relapse for 3-5 years (with a healthy way of life for the patient). In order to continue the period of remission, it is recommended to use the correct prophylaxis for non-productive use.

Combined therapy to pass the scheme: last 5-10 days ( very hot) I mean anti-tress drugs, like only the infusion of remission - immunomodulatory.

The drugs are divided into two types - roslinny and based on acyclovir. One way for the symptomatology of ailments, dulling them and translating into remission, and those - penetrating the infection of cells and blocking their reproduction and activity on DNA-derived (i.e. N. Chemotherapy).

Naybilsh often stagnate such drugs:

  • acyclovir;
  • ganciclovir;
  • Zovirax;
  • valacyclovir;
  • Ryativnik;
  • Panavir.

The preparation induces the activity of herpes-infected clitin, penetrating into their DNA. Healthy cells do not get cold. The vibe of a particular type is determined by the presence / absence of the virus to the new and anamnesis of the sick person. All speeches are issued in the form of powders for distribution for distribution of 250 and 500 mg.

Rules for storing Acyclovir and th analogs (Zoviraks, Ryativnik):

  1. Skin 250 mg powder is diluted in 10 ml of sterile water or 0.9% sodium chloride. In otrimany razchin add 40 ml of razchinnik.
  2. Dose for adults and children over 12 years old - 5 mg / kg of the patient's weight. Children of the young age doze out to change. The drug is not recommended for up to 3 months.
  3. Iakshcho in a sick person meningoencephalitis, herpes chickens, dozing up to 10 mg / kg.
  4. The maximum dobov dose is 30 mg / kg.
  5. Periodicity ін'єкцій - skin 8 years three for doba.
  6. Likas are introduced in droplets, trivially no less than a year.
  7. Play the therapy for 5-7 dB, and last for 3 days.
  8. Iakshcho ailments of malformations, immunodeficiency, a therapeutic course of trivial misyats, for which to switch to pills.

Vikoristannya valacyclovir. Precisely dosuvannya sign of lykar, ale add 450 mg once or twice a day. For children under 12, the drug is contraindicated. Lіkuvannya borrowed less than an hour, less with implantation of acyclovir.

Instructions for victorian ganciclovir:

  1. A necessary dose of speech is taken from a vial and reduced from 100 ml of infusion solution.
  2. The drug is administered internally, similarly to acyclovir (by volume).
  3. The dosage of the growth of the human population is 5 mg / kg, and the deficiency is 2.5 mg / kg.
  4. Acceptance of the liquor is carried out two for a day in equal hours and intervals (12 years).
  5. The triviality of the liking is 2-3 times.
  6. Yakshho Gantsiklovir of the signs of admitting therapy (in case of severe immunodeficiency), they take 5 mg / kg a day or 6 daily interruptions through the skin 5 dB.
  7. The patient needs to take a lot of driving.
  1. Panavir production is not required - it is sold in ampoules of 200 ml, which is recommended for growing up... The drug should be injected intravenously.
  2. The course is two in one, one to two days in one warehouse.
  3. If it is necessary, the therapy will be repeated every month.
  4. Herpetic infection in people with rheumatoid arthritis Likuyut more - you need 5 ін'кцій with the same intervals. Repeat the course in 2 months.
  5. For patients 12-18 years old, they will receive a change in addition. Children are younger than the drug of contraindications.

Important! Whether anti-tinea injections from herpes are contraindicated in the period of planned conception, before the hour of vaginosity during lactation. From an hour to the next hour, there is adequate contraception.

immunomodulators

Acyclovir and all the same old, as well as roslinny drugs (Panavir) are not good for strangling the herpes virus. Smell know the symptomatology, "suppress" the infection, ale less time. Relapse is not unique, even if the term appears, it can be pulled back, as the date of the immune system of shipping to the robot.

That will remain 20 years in the course of herpes infection. The drugs are used to mark the course of anti-tiering forces, to bring the natural energy back to the body, blocking the ability of this activity by itself.

In practice, in most cases there are injections of immunomodulators:

Likewise, in case of herpes lesions, it is recognized that there are other immunomodulators - Viferon, Amixin, Ridostin, Larifan, Kamedoni, Reaferon, Kagocel, Imunofan, Golovata, Likopid, Tamerid.

Anti-virus drugs are the basis for natural or synthetic pacing, which can be used for the treatment and prevention of foreign infections. The diya of bagatokh from them is vibrantly directed at the development stages of the viral infection life cycle virus.

In a given hour, there are more than 500 viruses, zbudnikiv zhoryuvan people. Virus revenge one- or double-stranded ribonucleic acid (RNA) or deoxyribonucleic acid (DNA), packed in a bilkovo shell - a capsid. The children of them have a shell of lipoproteins. Bagato virusi to revenge ferments or geni, to preserve reproduction in the family. At the bottom of the list of bacteria among the viruses of the neme vasnogo exchange of speech: the stench of the vicious metabolism of the patron saint of the patron saint.

RNA virus either synthesizes messenger RNA (mRNA), or RNA itself acts as a function of mRNA. Viruses are synthesized on them, including RNA-polymerase, for the participation of which mRNA is established by the virus. The transcription of the genome of some RNA viruses is found in the nucleus of the ruler's cell. On the basis of viral RNA, complementary DNA (provirus) is synthesized as a result of the reverse transcriptase of retroviruses, which is inserted into the genome of the patron saint. When transcripts are used, both the cell RNA and the mRNA of the virus are established, on which the virus is synthesized for the folding of new viruses. Viruses and incapacitation, as they are wicked, displayed in the table. 1.

Basic mechanisms of anti-tine drugs

At the stage of infection, the virus is adsorbed on the cell membrane and penetrates into the cell. In the course of a period of time, drugs become stagnant, which disrupt the whole process: detecting false receptors, antibodies to membrane receptors, ingibitories to viruses with a cell membrane.

At the stage of penetration of a virus, if a deproteinization of a virus and a "release" of a nucleoprotein is seen, an effective blocker of ion channels and a stabilizer of the capsid.

On the offensive stage, the internal synthesis of the internal components should be repaired. On a whole stage of effective ingibitories of viral DNA polymerase, RNA polymerase, vortex transcriptase, gelikazi, PRIMAZI, integration. On the translation of the international energy sources interferon (IFN), antisense oligonucleotides, ribozymes and Ingibitories of regulatory proteins. Into the proteolytic splitting, pour in ingibitori protase.

The IFN and the Ingibitories of Structural Bricks are actively pouring into the grain of the virus.

The conclusions of the stage are replicated to the cycle, including the trips of the daughters' verses from the clit and the bend of the infirmary cline-sovereign. On a whole stage of effective ingibitoria of neuronidase, anti-virus anti-lymphocyte and cytotoxic lymphocytes.

Find out about the classifications of anti-tier conditions. In this statistic, a classification was submitted for the inflow to the same virus (Table 2).

Antihypertensive and antihyperpetic drugs are easily recognizable.

Classification of anti-tier drugs, allowed until stashed on the territory of Russia.

  • group of anti-thyroid drugs:
    - Amantadin;
    - Arbidol;
    - Oseltamivir;
    - Remantadine.
  • Preparations for herpesvirus:
    - Alpizarin;
    - Acyclovir;
    - Bonafton;
    - Valacyclovir;
    - Gantsiklovir;
    - Glytsirrizinic acid;
    - Idoksuridin;
    - Penciclovir;
    - riodoxol;
    - Tebrofen;
    - Tromantadin;
    - Famcyclovir;
    - Florenal.
  • Antiretroviral drugs:
    - Abakavir;
    - Amprenavir;
    - Atazanavir;
    - Didanosin;
    - zalcitabin;
    - Zidovudine;
    - indinavir sulfate;
    - Lamivudine;
    - Nelfinavir;
    - Ritonavir;
    - Sakvinavir;
    - Stavudine;
    - Phosphazide;
    - Efavirents.
  • Іnshі anti-tartar preparations:
    - Inosine pranobex;
    - Interferon alpha;
    - Interferon alpha-2;
    - Interferon alpha-2b;
    - Interferon beta-1a;
    - Interferon beta-1b;
    - Yodantipyrine;
    - Ribavirin;
    - Tetraoxo-tetrahydronaphthalin (Oxolin);
    - Tiloron;
    - Flacoside.

Protigrypozny preparations (Table 2)

Arbidol is less than indole carboxylic acid. Mechanism for the drug is based on the suppression of the reproduction of the influenza virus, injected into the synthesis of IFN, the increase in the number of T-lymphocytes and the functional activity of macrophages, as well as the antioxidant effect.

The drug penetrates into the uninfected vigilante in noninfections, as well as in the infection of cells and appears in the nuclear and cytoplasmic fractions. Arbidol drives the process of lymphatic viral membrane with endosome membranes (at pH 7.4), which leads to the development of viral genome and ear to the process of transcription. In the name of amantadine and rimantadine, Arbidol brought the sound of the nucleocapsid itself to the name of the nucleocapsid, neuraminidazi and lipid shell. In such a rank, Arbidol din at the early stages of viral reproduction.

The specificity of the drug has a specific strain (in cultures the virus is attributed to influenza A virus by 80%, to influenza B virus - by 60%, and to influenza C virus - by 20%, human strains influenza virus).

Synthesis of IFN build-up, repaired from 1 tablet to 3 tablets. However, the forgiveness of the IFN level when receiving Arbidol is not spared. Shvidke build-up to the synthesis of IFN can press prophylactic activity when taking the drug until the ear is sick with influenza.

Arbidol is able to immunomodulate, leading to the backbone T-lymphocytes and T-helper. Moreover, the normalization of these indicators was spontaneous in patients with a decrease in the number of CD3- and CD4-clitin, and in particular with the normal functions of the clinny lanka, the immune system practically At the same time, Arbidol does not lead to an absolute decrease in the absolute number of T-supportive lymphocytes - such a rank that stimulates the activity of the drug is not tied to the function of supportive clitins. Arbidol has increased the number of macrophages with degraded bacteria and phagocytic number. To transfer, to activate stimuli for phagocytic cells, cytokines appeared, zokrema, IFN, products that could be adapted for the injection of the preparation. It is also possible to grow in the place of natural cillers - NK-clitin, which allows characterizing the preparation as an inducer of the activity of natural cillers.

The drug shvidko gets wet through the shlunkovo-intestinal tract (QCT). T 1/2 become 16-21 years old. It is excreted in an uncontrolled view of feces (38.9%) and slaughter (0.12%). With a sweep of the first, add 90% of the administered dose.

Likarskiy vzaєmodiyi Arbi-dolu with other medicinal preparations in the literature are not described.

Practically by the same side effects of the drug є allergic reactions... The drug permits until the end of the 2nd cycle.

Arbidol volodin to finish a wide range anti-virus activities and vikoristovuyutsya for the prevention and treatment of influenza types A and B, including those accelerated by bronchitis and pneumonia; gostrich respiratory ailments(ГРВІ); chronic bronchitis, Pneumonia, recurrent herpetic infections; v during the operational period- for normalization of the immune status and prophylaxis acceleration.

Amantadine and remantadine - lost to adamantane. The offense of drugs at low doses will cause the reproduction of the virus A. Oh, the anti-virus activity is supplemented by two mechanisms.

In the first place, there is a stench on the early stage of the viral reproduction, attracting the "razdyagannya" to the virus. The primary meta for cich preparations is block M 2 for influenza A virus, which forms an ionic channel in its shell. Applying the function of this library to ensure that the protons from the endosomes cannot be consumed in the middle of the virus, blocking the dissociation of the ribonuc-Leide and the transfer of the virus to the cytoplasm.

In a different way, the stench can take action and on the stage of folding the virus, mabut, for the process of processing hemaglutinin. The whole mechanism of mobility in children of strains of viruses.

Among the wild strains, there is a lot of resistance to preparations of winyk, protects from ailments, which accept them, and are treated with stiff strains. Sensitivity and style of viruses to amantadine and rimantadine is perechrish.

The offense of the drug is good to get wet when you take it all in the middle, it’s a great deal to get rid of. The great part of amantadine is vivoditsya from the section in the uninterrupted viglyad. The period of preparation (T 1/2) in young people is 12-18 years old, in young adults it is less important, and with a nirkovy lack it grows even more. This dose of the drug needs to be changed with insignificant changes in the function of nirok. Remantadine is actively metabolized in the liver, T 1/2 in the middle becomes 24-36 years old, 60-90% of the drug is vivified from the cross section in the metabolites.

When both drugs are taken, the most often mean insignificant dose-related damage to the side of the slunk-intestinal tract (tediousness, decreased appetite) and the central nervous system (CNS) (energy, sleeplessness, loss of concentration). When high doses of amantadine are taken, neurotoxic effects are more significant: fusion of symptoms, hallucinations, epileptic seizures, coma. The safety deposit for the hour of vaginosti has not been established. It is allowed to buy from 7-rychny vіku.

The drugs are stagnant for the prevention and elimination of influenza A. In a given hour, influenza permits the elimination of infections in 70-90% of cases. In individuals with persistent influenza A, use drugs lasting 5 days in vikovyh doses, chat on early stage sickness, by 1-2 to reduce the triviality of fever and distant symptoms, accelerating the disease and sooner period of seeing a virus.

Oseltamivir is an inactive alternator, which in the body transforms into an active metabolite - oseltamivir carboxylate. It is a transient analogue of sialic acid and a vibrating inhibitor of neurinidase viruses in influenza A and B. In addition, it was susceptible to viruses for influenza A, but before the preparation - older adamantane.

Neuraminidase to influenza virus cleaves off the endurance of sialic acids and, in such a rank, the ruin receptor, can be found on the surface of cells and new viruses, i.e. The active metabolite of oseltamivir wiklica changes in the active center of neuraminidase and drives activity. The aggregation of viruses on the surface of the cells is observed and the growth of the virus grows.

Stiyki strains to influenza A virus occur in 1-2% of ailments who take the drug. No persistent strains of influenza B virus were detected on this day.

When you take all the medication, it is good to get wet. Acceptance of їzhі doesn’t pour on its bioavailability, but it doesn’t reduce the risk of bitterness on the shlunkovo-intestinal tract. The drug is fed to enzymatic hydrolysis in the QCT and the liver using the active metabolism. Ossyag rozpodil drug close to the ossuary of birth in the body. T 1/2 oseltamivir and th active metabolite become 1-3 and 6-10 years, as appropriate. The offense is made by the head of the rank of nirkas in an unchanged viglyad.

When taking all the middle, there may be insignificant inappropriate views in the stomach and boredom, which changes when the drug is taken for an hour. Shlunkovo-intestinal dislocation tends to pass through 1-2 dib, to naviate any ailments I prodovuyu with the drug. There are no clinically significant interactions between oseltamivir and other drugs. The drug is used in children older than 1 year.

Oseltamivir is used for flu treatment and prevention. Prophylactic reception of oseltamivir during the period of epidemics reduces the incidence of those who are middle-vaccinated with the anti-thyroid vaccine, as well as those who are not vaccinated. In case of elimination of influenza with a drug, the drug is infused 1-2 times earlier, and the number of bacterial infections is reduced by 40-50%.

antiperspirant drugs

First, go to the negotiation of antiherpetic problems, it is necessary to solve the problem of herpes viruses and become ill, to suffer from them (Table 4). It is a pity that in the arsenals of modern anti-tartar drugs they use a number of medications, which can treat all viruses for herpes at once (Table 5).

Herpes simplex virus type 1 vicious damage to the shkiri, rota, trauma and brain, herpes simplex virus type 2 - lesion of the external organs, rectum, and corneal membranes... The first one from the admission of antihyperpetic drugs to the intake of antihyperpetic drugs is buv vidarabin (1977). However, with a glance at the temples, the toxicity of them was taken away for the treatment of illnesses, those with the herpes simplex virus and Varicella-zostervirus, deprived of life shown. Since 1982, for the elimination of ailments from mensh, an important overcoming of ailments has become the zastosovuvati acyclovir.

Acyclovir is an acyclic analogue of guanose, and valacyclovir is L-valynovium efir acyclovir. Acyclovir induces the synthesis of viral DNA from phosphorylation of viral thymidine kinase in all the other infected cells. The statements in the cells of acyclovirtriphosphate are absorbed into the DNA synthesized in the cells, to produce DNA until the growth of the virus lantsyug. A DNA molecule, before the storehouse, which includes acyclovir, is linked to DNA polymerase, irreversibly inactive.

The strength of a virus can be caused by a decrease in the activity of virus thymidynkinase and a change in virus DNA polymerase. The change in the activity of enzymes in vinicas as a result of mutations.

The bioavailability of acyclovir when taking it in the middle becomes only 10-30% and changes with increasing doses. On the basis of acyclovir, the bioavailability of valacyclovir at a rate of 70%. The drug shvidko and may be converted into acyclovir. Acyclovir penetrates into a rich biological age, including in the place of vesicles during vіtryanoї vіspi, Dorsal-cerebral ridin, accumulate in milk, near-mellow waters and placenta. Concentration of the yogo in the middle is in wide gaps. Syrovatkov's concentration to the drug in the mother of a newborn is approximately the same. It is practical not to get wet through the shkira drug. T 1/2 acyclovira to become in the middle in adults 2.5 hours, in new-born women - 4 years, in ailments with nirkovy deficiency, it can grow up to 20 hours. With vaginosis, the pharmacokinetics of the drug does not change.

As a rule, acyclovir is transferred well. When ointment is consumed on the basis of polyethylene glycol, it is possible to subtract mucous organs and see the liver. In case of vseredinu, the drug is vyklica head bolus, zamorochennya, visip and diarrhea. Nirkov deficiency and neurotoxicity are more common. The side effects of valacyclovir are similar to those of acyclovir - boring, diarrhea, headache; high dosages can be very difficult to intertwine with evidence, hallucinations, reduction of nirok and - even more rarely - thrombocytopenia. at internally introduced large doses of acyclovir may develop nirkoval deficiency and deterioration of the central nervous system.

Famciclovir itself is inactive, and when it is first passed through the oven it quickly transforms into penciclovir. Penciclovir is a tse acyclic analogue of guanosin. Mechanism for the drug is similar to the mechanism for acyclovir. Yak and acyclovir, penciclovir for the head rank for herpes simplex virus Varicella-zostervirus. Stay up to the penziklaviru in the classroom to create a little bit.

On the basis of penciclovir, the bioavailability of which, if only the middle, becomes less than 5%, famciclovir is good to get wet. With the acceptance of famcyklovir, the bioavailability of penciclovir growth is up to 65-77%. The reception of alcohol with the drug relies on the strength of the rest, but in general, the availability does not decrease. Osyag rozpodil penciclovir in 2 times and perevishag obsyag age in organizm, T 1/21/2 to grow up to 9.9 years. The drug is easily seen in hemodialysis.

To transfer acyclovir is good, but sometimes it is possible to diagnose a headache, boredom, diarrhea, cropping, and in young people - hallucination and confusion of svidomosty. preparations for mіssevogo zasosuvannya There may be a history of contact dermatitis and virazki.

The drug is safe for an hour of vaginosti, as well as the interaction of the drug with the other drugs has not been established.

Ganciclovir is a tse acyclic analogue of guanosin. Mechanism for the drug is similar to the mechanism for acyclovir. Active against all herpesviruses, but most effective against cytomegalovirus.

The bioavailability of the ganciclovir in the middle of the hour becomes 6-9% and is less than in the middle of the heart. Valganciclovir is kindly to get wet and quickly go to ganciclovir, the bioavailability of such growth is up to 61%. With the intake of valganciclovir for an hour and a half, the availability of ganciclovir increases by 25%. In case of normal function of Nirk T 1/2, become 2-4 hours. More than 90% of the drug is administered with Nirk in an uninterrupted viglyad. With a nirkovy deficiency, T 1/2 grows up to 28-40 years.

main dosage side effect gancicloviru - blood formation (neutropenia, thrombocytopenia). In 5-15% of the ailments, it is obvious that the central nervous system is affected at a lower stage of severity (from a headache before the court and Komi). With internal introduction, there may be phlebitis, azotemia, anemia, visipa, fever, change of biochemical indicators of the liver, boring, bloating, eosinophilia.

In laboratory brews, the drug has been inflicted with a teratogenic and membranous toxicity, irreversibly destroyed reproductive function... Cytostatic drugs pobichna diya ganciclovir on the cystic brain.

Idoksuridin is an iodine analogue of thymidine. Mechanism of anti-Russian development until the end of the day At the same time, the phosphorylation of the lost drug will be absorbed into the virus and the cell of the DNA, but it will not cause a replication of the virus. With a large amount of DNA, it becomes more crying, it is easy to collapse, with transcription, it is often grateful. They are seen as a person with herpetic keratitis, as they have eliminated idoxuridine. The drug permits liche for muscular zasosuvannya. At the same time, there is a lot of energy, sverbinnya, firing and filling in the area of ​​the eyes, allergic reactions.

The successes of antimicrobial therapy of the 20th century led to a general control over bacterial infections. Heads of Infectious Diseases and Pharmacologists of the 21st Century Ensuring control over viral infections. In addition to the high efficiency, the new anti-tier drugs are guilty of being well tolerated. In the present hour, new technologies are being developed with fundamentally new mechanisms. It is promising to find a way to strangle pathological immune reactions and immunotherapy with monoclonal antibodies and vaccines.

N. M. Kiselova, candidate medical sciences, assistant professor
L. G. Kuzmenko, Doctor of Medical Sciences, Professor
Russian State Medical University, Moscow

Herpetic anxiety is very difficult to get rid of for additional ointments and tablets, but not everyone knows how to get injections like herpes. As a rule, to a large extent to the likelihood of a problem, the infection often starts to recur and expand on a large number of cases.

Pidbirati and іn'єktsіynі lіkarskі is necessary for urahuvannya zagalny camp of ailing and individual specialties. Far from all situations are the same, however, it is good to help patients with analogous diagnoses, to find some of the most common symptoms that are quite similar.

What vipadas are recognized?

Vikoristannya injections against herpes can be known in offensive infections:

  • if on gostromu step getting sick is not being adequately treated;
  • with severe immunodeficiency;
  • if the check is promptly received by the patient;
  • if great infectious processes are spared, too, equal organ, Brain and hepatobiliary area;
  • all frequent recurrences of relapses of illnesses;
  • in case of sexual partner information;
  • with degenerative-destructive lesion of peripheral nerves;
  • in case of collapse, abo the seeding of the processes;
  • in females with herpes virus infection in a combination of IDPs.

Ін'єкції Ін'кції due to herpetic infections іnfektsії to prevent serious infusion on the body. Therapy can be used for additional immunostimulating or anti-tine drugs, as well as combined drugs pharmacological activities overnight. Correctly organized therapy є with a lock-up of a trivial period, if the virus will be in the "sleeping" camp and will not manifest itself in the presence of pathological symptoms.

Otzhe, are the injections for herpes effective?

anti-virus drugs

All the anti-tiers are available for the іn'єktsіyny victorious party to be divided into two categories:

  • roslinnі, as zdatnі usunuti signs of illness і translate the virus into a trivale inactive camp;
  • inorganic, viroblen on the basis of acyclovir, which penetrate to the structures of genital cells, show functionality on the basis of DNA, allowing the virus to multiply.

Infections against herpetic infections successfully stop and prevent recurrence of pathology, accelerate the regeneration process shkіrnogo coverі mucous, reduce the frequency and severity of pathological manifestations of ailments and increase the spread of the virus to sick people.

Injections from herpes need to be taken from the treatment of the stiffness of a particular type of virus before them. On the health of the cells, do not infuse medications with medications.

name

Popular lіkuvalny drugs:

  • "Panavir";
  • "Zovirak";
  • "Acyclovir";
  • "Medovir";
  • "Ryativnik".

Name the injections for herpes as a bagate.

"Panavir"

It is against the grain of the disease to take the biologically active element - hexose glucoside, which can be found in Solanum tuberosum. Wine is a high-molecular polysaccharide, which is a higher level of extravagant organism up to the development of agnostic old wines and the growth of blood-borne interferon by blood cells. Krym tsyogo, the wine is insignificant for the fiery fiery dyu.

With parenteral administration of a medical method, the speech at a high concentration appears in the plasma after 5 chilines. Vivedennya to the medication will be repaired approximately through p_vgodini. Winning organism through a secular system and a dichotomy. Liki "Panavir" is recommended until stasis in the following situations:

  1. With the development of pathologies, infected with herpesvirus (including oral, intramural and genetic), IDPs (including the diagnosis of gostrich condylomas), as well as DNA and RNA enteroviruses.
  2. With cytomegalovirus infection in women.
  3. With damaged functions immune system on the smallest infectious diseases for them.
  4. With local defects of the mucous membrane of the gastroduodenal zone, natural in Russian infections, Which are transmitted by clamps, ignition processes in the prostate of bacterial progression and autoimmune diseases of loam and susceptible tissues in the presence of recurrent herpesvirus.

When infected with herpesvirus of the first and another type, it is usually recognized, as a rule, 2 "panavir" (5 ml) with an interval of 24 years or two dobi. If it’s a necessity, the therapy will be repeated for more than one month.

Pharmacological status "Panavir" is administered internally. It is not possible to collect the whole syringe in one syringe. The introduction of the medication was guilty of being strumenev and duzhe povilny.

How many injections are there for herpes to become stagnant?

"Acyclovir"

danish medication actively stagnate against herpes Ⅰ type. It is eligible for herpetic infections on genitalia, as well as in the form of operative lichen. The parenteral form is a lyophilizate with an active element, which can be used for infusion. A small bottle of skin should be given 250 mg of acyclovir in sodium chloride vigor.

For adults and children, they recognize the droplets with acyclovir, or else they should be able to use the medication internally. Rozrakhunok dosuvannya is carried out individually with urahuvannya masti tila and viku sick. The interval between the introduced ones is responsible for becoming 8 years. For parenteral vikoristannya instead of a vial, it is necessary to break it in 10 ml of ін'єкційної water and even in physiological form.

As long as likarskiy zasib is introduced by the method of strumming, then such a zakid can be carried out even more often (for an hour - about 60 khvili). If the liquor is injected in drops, then the medicinal product should be distributed in the same way (the zagalny obsyag is guilty of the area of ​​50 ml).

If necessary, the introduction of the drug in high doses (up to 1000 mg), the amount of the administered dose is proportionally increased. The triviality of a therapeutic course is to lie down as a patient and his reaction during the treatment. Ін'єкції zdіysnyuyutsya, as a rule, stretching 7 days.

Yak injections for the treatment of herpes will become stagnant with immunomodulatory medications.

immunomodulatory medicines

Immunity of prey is organism from aggressive pathogens and internal aggression (autoimmune processes). One of the ways to improve immunity is to change the level of T and B cell lymphocytes in the body, to decrease their functional activity, to change the robot's development of monocyte and viral processes.

An anti-virus therapy for the treatment of pathology is based on the correction of antibiotic viral therapy and the process of phagocytosis. Immunoglobulin and interferon are widely used as injections for herpes.

Name it like this:

  • "Vitagerpavak";
  • "Taktivin";
  • "Immunoglobulin";
  • "Timogen";
  • "Imunofan";
  • "Golovata";
  • "Polyoxidoniy";
  • Cycloferon;
  • Ferrovir.

"Vitagerpavak"

Tsey medication є antihyperpetic vaccine and vicorisation in the treatment and prevention of herpes simplex aggravation.

Unimportant to those who do not want to see them. of this affliction, Vona maє bezlich perevag:

  • clerical immunity;
  • seizure of relapses;
  • do not rob toxic injections.

The drug is administered as a pediatric one at the beginning of the meal in a volume of 0.2 ml. The course of injections for herpes is responsible for the area 5 ін'кцій - every 7 days.

"Immunoglobulin"

Active words are anti-herpes antigens, as well as neutralize them. In case of recurrence or primary infection, the drug is administered internally, 1.5 ml every 3 days. For a secondary course, you need to make these injections. To improve the efficiency of the Danes, Likarskiy zasisovuyt mіstsevo - rozchin vykorystovuyutsya for obrobovyh vypiruyu vyipan in the zone of genitalіy.

In the zone of rhizik there are women who are protected from the preparation given to the drug only after the first trimester. It should be administered internally according to the same schemes, as for the other patients, but for a therapeutic course of maybutnoy mother to reach six injections. In order to be afraid of interruption and to repeat the course during the same period of 36 years.

PVS is stagnant for prevention and treatment of illnesses, viral infections.

V. є the henchmen of a great number of illnesses from the mass to the ridky, exotic (influenza, GDVI, cyr, herpes, hepatitis, rubella, vispa, mumps, poliomyulitis, SNID ...).

V. - multiple nucleoprotein parts, which are stored in DNA molecules or RNA + blocks. Infecting part - DNA, RNA. Vona penetrates into the middle of the cell (behind the mechanism of exocytosis) and there it will start to re-energize the system of metabolic processes in the cell of the ruler.

Mechanisms of anti-tiering activities begin with stages of development of viral infections.

    The "gateway" of the infection is the mucous membrane and the skin, or without the middle virus it is consumed in the roof (oxolin ointment).

    Virus penetrates into the roof, spread through the body → tissue-targets. It can be infused on the virus, in the blood circulating (interferon and anti-virus AT = immunoglobulin)

    The stage of penetrating the virus into the target's cell. The virus penetrates into any mice, and only clinks in the singing muscle of the cell membrane - with the glycoproteins, which are the noses of the virus. You can: a) re-attach the attachment (adhesion) of the virus to the membrane of the cell and galmuvate penetration into the cell of the ruler; b) driving the deproteinization of the viral genome (remantadine)

    the stage of propagation of viruses in the cells of the virus in the introduction into the synthetic processes of the cell-haze and the growth of DNA and RNA. Deyaki viruses (herpes simplex), having penetrated into the cell of the ruler, repair their enzyme, which is generated from analogous enzymes in the cell of the ruler (DNA - polymerase).

Suffocation of the breeding of viruses:

    attributable to the synthesis of vernier bilks: a) "early" bilks - enzymes, b) "pizni" bilks.

    Principle of viral DNA and RNA synthesis.

So even more drugs (virazol, acyclovir ...)

    Determination of viruses - informational clitin, which will be able to establish new viruses (interferoni).

Including for prevention V.I. it is necessary to prevent the penetration of viruses into the cells of the target (1, 2, 3), and for the treatment - to disrupt the mechanisms of synthesis of viral proteins and nucleic acids (4) + (5).

Viral infections, as a rule, develop against the background of reduced immunity. Tom preventive measures V.I. - anti-tier immunity:

A) Specific immunosacist - vaccines, immunoglobulin (AT), interferon.

Virusnі bіlki - sіnnie AG. In the body, as there is a flow of viruses, INF and AT are viroblyayut, which neutralize the viruses.

B) Nonspecific immunity - adjustment of stiffness up to Infectious diseases as a whole. Immunomodulators, inductors INF, vitamins, adaptogen ...

I. Protigerpetic cousins.

There is a large group of anti-tier forces. Herpes virus can be divided into groups, from urahuvannyy you can get sick:

A) B. herpes simplex : HSV-1 - skin, mucous membranes, HSV-2 - genitalia, eyes, central nervous system.

B) V. Garicella Zoster - operative herpes (adults), vitriana vispa (children), operative lichen.

V) cytomegalovirus - retinitis, colitis, pneumonia, internal uterine infections, generalized infections, infections caused by organ transplantation and infection.

In total 8 types of viruses in human herpes, the disease is malignant, right up to lethal form.

More than 90% of the population of the earth is diagnosed with the smallest types of herpes virus. The Russian Federation regularly has HSV infections of more than 15 million.

Transmitted by drip-droplet and contact path.

Likuvannya - Mistsevo. Iakshko sickness often, at least 4 times on the risk - in the middle, immunity, systemically. Herpetic infections do not develop. The primary virus infection is predominantly lingering in the body, saving health before reactivation.

Herpes- in the cross-section "rattling", so 2300 years of that ailment was called Hippocrates.

simple : First infections in a child's life. Infection from 1 - up to 4 years of life for the growth of temporary contacts with grown-ups. After 2 years, after the contact, the virus penetrates into the skin and reaches the beeps of the tripartite nerve, which interferes with the skin of the denouncement. having penetrated into nerve tissue Penetrates into the empty skull and occasionally gets lost in the ganglia tripartite nerve... There he was in a "splash" until the moment of reactivation (cold, flu, menstruation, stress, hectic, more UV-optimized and іn. Umovi ↓ immunity ..).

Three lips can be found on the inner part of the body (eyes, oral sex, ... forehead, cheeks, vuha ...).

Virus not to love UV, alcohol, Antiseptics ...

herpes of the central nervous system - navazhcha infection of the central nervous system. Mortality is 70%, functional renewal in 9%.

herpes zoster - ailments grew older they got sick on the weekends. shkirni visipi on one side of the body, without a little bulbs, filled with age, even more painfully, a little bit of pain + headaches, tº, pain in the legs, ridge ...

Nucleide analogs.

Synthetic lost nucleosides may bend with a vibrating antiherpetic drug.

Mechanism of action: antiherpetic action is not the speech itself, but its active metabolism - triphosphate. In a patient with a virus, three molecules of phosphate are taken before the drug. The solution to the virus is not connected to the virus DNA polymerase, to be added to the DNA virus (substitute deoxyguanosine, but also to the virus), and it is necessary to add a replica to the DNA polymerase (it is not necessary to reduce the amount of such DNA to the virus).

ZF = L - F - F - F

Healthy cells have concentration

triphosphate 50-100 times lower, lower

cells infected with a virus, that is why

imparting first phosphate

use an enzyme, like

є tilki in virus herpes = virus

timinkinaza.

Acceptance of the 2nd and 3rd phosphates is produced by the enzymes of the cellini = kinases, and not the virus. Tobto a therapeutic dose is not suitable for a healthy clitina, only for ailments.

Such preparations are the most effective in the early term of becoming ill (1-3 days), so that viruses actively proliferate. Diya is prophylactic and lykuvalny.

ACYCLOVIR(Zoryraks, virolex, tsilovir ...) - is not guanosin.

Dіyucha speech acyclovir triphosphate, which is added to the virus DNA to replace deoxyguanosine.

F. to. bioavailability in case of reception is all the way low 15-20%, moreover, it will rise: penetrate into the slime, internal fluid, vaginal secretion, central nervous system, into the area of ​​herpetic puffiness. Slightly get wet with muscular zasosuvanny.

spectrum: Most activity in the type of HSV_1,2, weaker on VH, Zoster and is insensitive to cytomegaviruses.

PC: A) infectious diseases of HPV - shkіra, mucous, eyes, genital herpetic encephalitis

b) operative lichen, vitriana vispa

c) with prophylactic treatment in ailments with VD (recurrent forms)

F.V. cream 5%, intramural ointment 3%, tabl, 0.02, 0.04, 0.08, capsules 0.02, ampoules with powder for preparation of rosin (0.25, 0.5, 1.0). Course 7-10 days × 5 r / day.

PBB: Low toxicity.

Mistsevo - pechinnya, sverbіzh, phlebiti.

Systemic - slunk-intestinal tract, IV - nephrotoxicity, neurotoxicity (sudom, malnutrition, extrapiracy, headaches, etc.)

The acyclovir is required to recognize the yakomog earlier, at the lower stages, mayzhe is inactive.

VALANTSIKLOVIR(Valtrex) - valinoviy efir acycloviru. The meanings for the reception are all in the middle. The bioavailability is very high, more than 50% (the ether is removed in the body, so that the concentration of acyclovir in the tissues is liquefied).

PC Infections HSV - especially genital, operative versicolor and in.

F.V. tab. 0.5 × 2 r / d. Course 7-10 days.

penciclovir(Vektavar) - for Budova, the spectrum of activity is close to acyclovir.

visibility :

    Actively recognizable acyclovirresistant strains of viruses

    More effective at lower stages H

    Big trivial T1 / 2 in the middle of the village (7-20 years old), tobto pratsyuє 12 years

    Vikoristovuyt tilki mistsevo

PC: Herpes of shkiri and mucous membranes.

F. In... cream 1% × 2 r / d course for 4 days.

FANTSIKLOVIR(Famvir) - bioavailability 70-80%. In the body (blood, intestines, liver), it transforms into penciclovir → P-triphosphate, it is secreted by 70% with nirkami in active viglyad.

spectrum: Seeing viruses in herpes.

PC: Recurrent genital herpes, herpes ovaries, postherpetic neuralgia.

F. In... tab. 0.25.

PBB: Dyspepsia, neurotoxicity.

ganciclovir

spectrum: Din for cytomegalovirus. At 10-15 times more hematological.

F. to. to get wet from the shlunkovo-intestinal tract is rotten, alas, it’s okay to get into the small fabrics. Vivoditsya nirkami.

PC: Retinitis, pneumonia, lesion of the intestinal tract, IMV - β - infections in patients with SNID.

PBB Often, ≈ in 1/3 of the patients є the cause of the swelling (hepatotoxicity, CVS, nephrotoxicity, neurotoxicity, intestinal tract, phlebitis).

F. In... 0.25 capsules, bottles, powder for ін'єкцій.

IDOKSUREDIN(Oftan-IDU) for a budova analogue of timidin.

PC: Visoka activity in muscular lysis of herpetic lesions of the eyes (keratitis, conjunctivitis)

F. In... ochn_ drops 0.1% solution, bury skin for 2 years.

PBB: Rozdratuvannya, b_l, clod of mucous membranes.

With resorptive dії (i / v) effective with generalized herpes. Ale duzhe temporal toxicity (↓ leukopoiesis)

ROSLINNI ZASOBI

alpizarina- speech of a roselinnogo podrodzhennya (a copy of the grass, a mango leaf). For a cheery budova, xanthone (analogue to Vitamin R).

Driving DNA multiplication-revenge

virus. MA protivirynu, anti-

bacterial, immunomodulating

About dina.

F.V.: tab. 0.1, ointment 5% - skin, 2% - mucus.

PC: Herpes simplex of shkіri і mucous membranes, herpes Zoster (prostate, genital 2, vitriana vіspa, operіzuvalny lichen, warts, candidiasis).

In the middle x 3-4 w / d - 5-10 days. overnight

Ointment x 3-3 r / d - 10-30 days

You can vikoristovuvati tablets with prophylactic methyu.

Glitsirizinova ACID

Mechanism of development: a) ↓ synthesis of internal bottles and in. Components in the detection of cells, b) inactive virus pose of the cell, c) blocking the virus in the middle of the cell.

PC: Infections, viral infections with simple hepatitis 1 and 2 (skin, mucus mouth, nose ... genital herpes), herpes zoster and in.

PBG: allergic reactions

FV: spray, cream, vaginal form.

FLAKOZID- from the leaf of roslin to oxamite (Amur, Laval) this. Rutovikh.

For budova similar to alpizarin.

PC: primary or recurrent herpes simplex (early stage).

F.V.: tab. 0.1 x 3 r / d, course 5 days. and more.

Roncoleukin (recombinant interleukin-2) can be found in the complex treatment of herpetic infections in older forms and at the younger stages of illness.

II. FOODS FOR LIKUVANNYA GRIPU I GRVІ.

amantadine- the first preparation with added anti-weed

RMANTADIN activity. This year's PC is not victorious.

On the basis of rimantadine breakdowns in the Russian Federation.

Mechanism of development: blocking of special channels (M 2 -channels) to the virus, as a result, the ability to penetrate into the cell will be destroyed. M 2-channel - a block, the appearance of a virus only for influenza and a rise in the virus genome in the cell (M 2 - viral “spreading” to a virus = deproteinization).

FC: good to get wet and grow up when you get into the middle, penetrate into the central nervous system, high concentrations in the mucous nasal passages and slugs; oven; nirki.

spectrum: virus to influenza A (є stiyki shtami).

PC: a) prophylaxis 0.5 x1 r / d or 0.1 x2 r / d - the course is 14 days.

b) lykuvannya at the early stages of 0.1 x2 p / dob or according to the scheme

PBG: dyspepsia, abdominal pain, central nervous system, shkirni visipi.

PPK: liver, nirki, thyrotoxicosis, vagina.

F.V.: tab. 0.05 "Algirem" - syrup for children.

Shvidko vinikaє zvikannya (up to 5 days up to 30%).

Swine flu = pandemic flu. Remantadine is not dіє.

oseltamivir- visoka specificity, on some viruses it is not

zanamivir diyut. I mean in the first 24-48 years when symptoms appear.

They are similar to the mechanism of production.

Mechanism of Diya: Attract an active neuromedase, an enzyme that is indicative of the process of vivification of new-made virus particles from infected cells, penetrating into the cell's food dikhalnyh nobles and further expansion of the virus into the body.

PC: Influenza type A and B + pandemic flu.

Zanamіvіr - lіkuvannya. F.V.: іngalyatsіyno- rotodiski, scho to revenge 0.005 single dose. Ingalyats_yno, to that it is nasty to get wet from the shlunkovo-intestinal tract (inhale the powder). With muscular stasis, PBS is rare (dyspepsia, headache, bronchospasm - with schilosti). I mean z 5 rockiv 2 r / d, course 5 days. No resistance.

Oseltamivir (about liquids) - good to get wet, bioavailability 75-80%. High concentrations in the middle of influenza infections. Children from 1 rock.

PBB: Dyspepsia, headache, weakness, sleep disturbance (often less in zanamivyr), sore throat, cough.

F.V. capsules 0.075.

Likuvannya and prevention of influenza. Chastkov resistance to pandemic influenza.

ARBIDOL- lost endokh. I’m going to fight against Russian diyu, іnterferonіv inductor, іmunomodullyuyuchu dіyu; advances the organism's stiffness to external infections.

PC: Non-specific prophylaxis and treatment of influenza A and B, GDVI.

F.V. tab. 0.1, treatment x 3-4 w / d 3-5 days, prophylaxis x 1 w / d 10-14 days.

PBB: Allergy.

PPK: ССС, pechinku, nirki.

oxolin- old naphthalene, old drug.

Mechanism of Diya: ≈ yak at remantadine (for the last virus).

Pomirna virusotsidnoe diyu.

PC: 1) flu prevention

    virusnі urazheniya eyes

3) viral rhinitis

4) projection of shkiri

F. In... oxalinova ointment - 0.25%, 3%

With influenza, cover the mucus membrane of the nose x 2-3 r / d

PBB: Printing on the drawing.

For the treatment and prevention of influenza, you can use vicoristani:

Interferon alfa-2v(Gripferon) (recombinant drug) - drops in nis. Viferon

Inductor INF: " Anaferon"- homeopathy

Cieloferon

Kagocel

Arbidol

 


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