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  Helps get rid of pruritus. Common causes of itching and types of medication for pruritus

Pruritus and an irresistible desire to scratch, is a frequent companion of many allergic, inflammatory and infectious diseases skin integument  and internal organs. The treatment is individual, complex and always directed at the root cause of the disease.

Itching occurs as a result of irritation of the nerve receptors of the skin by special biologically active substances, which, as a result of certain reactions, transmit a signal to spinal cord, and from there - to the cerebral cortex, where this feeling is processed and leads to certain actions.

Many preparations for itching exert their effect on the effect of biologically active substances of the human body. These are special chemical compounds that contribute to the feeling of itching. Antipruritic drugs block their formation or release from the cells of the body.

A small group of drugs for itching can suppress nerve impulses or increase the threshold of sensitivity in the nerve endings, thereby affecting the problem at the level of the nervous system.

The main biologically active substances that cause itching are the following:

  • histamine;
  • bile acids (especially relevant in the pathology of the hepatobiliary area);
  • uric acid;
  • serotonin;
  • opioids;
  • various cytokines secreted by inflammatory reactions.

Common causes

The reasons pruritus  It is very important to recognize and know, since the effectiveness and duration of treatment will directly depend on it. It is customary to distinguish two main groups of causal factors:

  1. Common diseases (manifested by generalized itching).
  2. Skin disease (manifested localized itching).

Dermatological diseases


The main dermatological diseases that lead to this unpleasant feeling are the following:

  • hives;
  • scabies;
  • pediculosis;
  • eczema;
  • seborrhea;
  • skin mycoses;
  • atopic dermatitis.

Localized

  • Anal - with hemorrhoids, helminthiasis, anal fissure.
  • Vaginal, caused by candidiasis, lack of estrogen in a woman's body, especially during menopause.

Generalized

The following pathological processes lead to generalized itching of the skin:

  • renal failure, leading to impaired excretion of uric acid and many products of nitrogen metabolism in the body;
  • cholestasis (stagnation of bile) against the background of either edema of the biliary tract (with hepatitis, cholecystitis), or as a result of blockage with stone (with gallstone disease);
  • hormonal changes during pregnancy;
  • blood diseases - polycythemia vera, lymphogranulomatosis (for it, pruritus is one of the earliest manifestations);
  • diseases of the endocrine glands - diabetes, hyper and hypothyroidism.

Drug

There are certain drugs that are provocateurs of pruritus.These include:

  • erythromycin;
  • estrogens, including oral contraceptives;
  • phenothiazines.

Such detailed detailing of causative factors is necessary for the proper selection of treatment. It depends on the specific mechanism of development of pruritus.


Drugs and treatment guidelines

Treatment of pruritus depends on the specific cause that led to its development. Tablets and other therapeutic agents are selected based on the mechanism of itching (pathogenetic therapy). In parallel, the main cause, that is, the background pathological process (etiotropic therapy), is eliminated as far as possible.

Principles of treatment

Treatment involves the implementation of general recommendations:

  • eliminate exposure high temperatures  on the skin, it is recommended to be in a cool room;
  • do not wear synthetic and woolen clothes;
  • avoid substances that expand vessels - alcohol, coffee;
  • after taking a bath or shower, be sure to moisturize the skin with special means;
  • use only soaps and gels with low acid-base balance.

Drug Requirements

The agent used for treatment must meet the following requirements:

  • effectively eliminate pruritus;
  • do not call side effects  or they should be minor;
  • if possible, it should be long-lasting, so that the multiplicity of reception was no more than 1-2 times per day.

Main groups


The main pharmacological agents for the treatment of pruritus are the following:

  1. Antihistamines.
  2. Corticosteroids.
  3. Topical anesthetics.
  4. Calceneurine inhibitors.
  5. Cholestyramine, which binds bile acids.
  6. Opioid receptor blocker.

Antihistamines

As can be seen from their names, they block the mechanism of histamine action. This is accompanied by a decrease in capillary permeability, a decrease in edema, a decrease in redness and, as a result of all these processes, an antipruritic effect that develops half an hour after oral administration. The main drugs in this group are:

1. Antihistamines of the first generation, it is Chloropyramine (Suprastin), Diphenhydramine (Diphenhydramine) and Clemastin (Tavegil). These drugs relieve itching well, but have a number of side effects that limit their use. TO side effects  include drowsiness, lethargy and decreased concentration.

2. Antihistamines of the second and third generationthat do not affect the central nervous system and do not cause drowsiness and decrease in attention - Cetirizine, Ebastine, Loratadine, Fexofenadhydrochloride.

3. Tricyclic antidepressants, for example, Doxepin and Amitriptyline.

Antihistamines as an anti-pruritic agent are preferred for the allergic form of this symptom. With common diseases, they are usually not effective.

Corticosteroids

Glucocorticosteroids (Prednisolone, Betapred) are mainly used in the form of local forms - ointments applied to the skin. Prolonged use of hormonal ointments can lead to atrophic changes in the skin.


In the case of severe itching, when local corticosteroids are not effective, their systemic administration can be used. In generalized itching caused by allergies, these agents are effective, but the dosage, duration and general condition of the body should be strictly observed.

Improper use of hormonal drugs can disrupt the internal balance of the body and lead to irreparable consequences. In this case, the course of treatment should be short - one or two weeks, since there is a high probability of serious side effects.

The use of local anesthetics for itching is justified. They cause a non-specific blockade of nerve impulses at the level of sensory nerve endings. Their effectiveness is enhanced if cooling agents such as menthol are used in combination with them.

Calcineurin inhibitors

These drugs are new antipruritic agents. They inhibit the enzyme that is involved in the process of calcium transfer into the cell, which is observed in inflammatory reactions. Therefore, their use blocks pro-inflammatory cytokines, which lead to itching of the skin. They also block selection. inflammatory mediatorssuch as histamine, serotonin and others. These drugs come in the form of local dosage forms  - Elidel ointment, Tacrolimus. Their use is shown as a means of the second line when inflammatory itchwhen traditional remedies are not effective or cause unwanted side effects.

Cholestyramine

The use of Cholestyramine is justified in the pathology of the hepatobiliary system. It absorbs bile acids on itself, forming insoluble complexes that are eliminated from the body. In case of prolonged use, absorption of fats and fat-soluble vitamins is impaired, which leads to A, D, E and K hypovitaminosis, as well as constipation.


Opioid receptor blocker

Naltrexone as an opiate receptor blocker can be used in those patients in whom the standard drugs do not bring the desired result in the fight against generalized pruritus. Developing side effects of their own pass, which should not limit the use of this pharmacological agents. They can be headaches, jerky muscle twitches, nausea, vomiting, and dry mouth.

Additional methods

These types of pruritus therapy are:

  • ultraviolet phototherapy;
  • phytotherapy - use medicinal plants  (mint, chamomile and others), which are added to a warm bath (but not to a hot one);
  • diet therapy;
  • acupuncture and some others.

In conclusion, it should be noted that the choice of a particular drug depends on the causes and mechanisms of development of pruritus. Not all available antipruritic drugs are effective. It depends on the specific causative factor in one or another clinical form. Each group pharmacological drugs  It has an effect on a certain factor, with which they associate the low efficacy of some drugs in the treatment of itching and the high of others.

Itching is extremely unpleasant, and sometimes just a painful sign that any person who has encountered it wants to get rid of as soon as possible. Find out possible reasons  this symptom and the main methods of its elimination.

What is itching, how does it manifest?

Before enumerating the manifestations of itching, it is worth to understand the mechanism of its occurrence. It usually develops due to irritation of the nerve receptors that literally penetrate the skin. They can be affected by various substances transported with blood and present in it in high concentrations.

These may be responsible for reactions to stimuli and allergens histidine and histamine, produced by the liver and not having time to get bile acids out of the body, some slag or toxic substances, endorphin and serotonin hormones, as well as enzymes synthesized by the body and other components.

Depending on the mechanism of occurrence of itching, there are the following types of it:

  • Physiological itching occurs as a result of a direct impact on the skin, for example, insects crawling on it or tickling.
  • Proprioceptive pruritus occurs after irritation of the so-called proprioceptors, which are responsible for the sensitivity of the skin, for example, after insect bites.
  • Neuropathic itching develops when exposed to nerve endings, fibers or receptors, and can occur in various diseases.
  • Neurogenic pruritus does not depend on the nerve trunks and has a central genesis.
  • Psychogenic itching can occur on the background of phobias or mental disorders, for example, fear of crawling insects.
  • Mixed form combines several species.

Itching manifests itself in the form of a strong desire to scratch the skin, and it can be both localized and affecting a particular limited area of ​​the body, as well as extensive and widespread, covering almost the entire surface of the skin. Likely to occur discomfort  on the face, hands, scalp, palms, feet, thighs, legs, chest, back, in groin area, near the anus, between the fingers.

Often this symptom is accompanied by others: red spots, burning, redness, redness, rash, swelling, peeling and dryness. The expressiveness of sensations can also be different: sometimes itching is mild, sometimes it is just painful, causing discomfort and suffering and forcing you to comb an itchy place into blood.

Why does itch it?

The reasons for which there is a strong or, conversely, slight itching of the skin, are many and varied:


To eliminate the symptom itself and the relief of the condition, you can use some local pharmacy drugs. For bites and allergic reactions, antihistamine gels and creams are used, for example, Fenistil. In dermatological diseases, zinc-based drugs are effective. In severe cases, corticosteroids are prescribed.

To quickly relieve itching, you need to follow the rules of personal hygiene. It is especially important to take a shower regularly, but without using aggressive detergents. Lightened condition cool water. The room in which the person resides should often be ventilated and, if necessary, humidified if the air is dry (or, on the contrary, dried at high humidity).

Will help eliminate unpleasant manifestations folk remedies:

  • Use for rubbing, lotions and compresses decoctions of medicinal plants, especially the series, the bark of oak, sage, chamomile. They can also be added to the bath.
  • Treat the itchy areas with a weak soda solution (a teaspoon of powder to a glass of cool water).
  • Will help essential oils  mint, eucalyptus and tea tree, dissolved in water or basic natural oils: peach, almond, olive.
  • You can treat the skin with aloe juice.

If you encounter such an unpleasant symptom as an itch, find out its causes and begin to act as soon as possible to alleviate your condition.

Pruritus  - a sensation that causes the need to comb the skin.

Causes of pruritus.

In most cases, it has neuro-allergic causes. It may be a symptom of various skin diseases (eczema, urticaria, scabies, and others) or an independent skin disease (the so-called idiopathic pruritus). Itching may be due to intolerance to certain foods, sensitivity to drugs (antibiotics, sulfonamides), a response to changes in external temperature (cold itching and heat itching). In old age, itching may be the result of dry skin. Itching is often a consequence of severe common diseases  (hepatitis, diabetes, leukemia). The itch can be at various neuropsychiatric diseases - neurosis, manic-depressive psychosis. Sometimes itching is felt on limited areas of the skin, most often in the genital area (for example, with prostatitis), anus (with hemorrhoids, worms), and hair of the head (with seborrhea).

Symptoms of pruritus.

Itching may be persistent or paroxysmal. Itching usually increases in the evening and often becomes unbearable. Scratching remains on itchy areas of the skin, with persistent long-lasting itching, the nails of the hands often change: a mirror-like shine (polished nails) and a free edge appear.

Treatment of pruritus.

First of all, you need to get rid of the cause that caused itching. A special diet with the exception of irritating products, sedatives, anti-allergic drugs. Helps warm baths, alcohol wiping with menthol, corticosteroid ointment.

DRUGS FOR THE SKIN TREAT (APPOINTED DOCTOR)

Antiallergic drugs
Diphenhydramine
Ketotifen (Astafen, Broniten, Zaditen, Ketasma, Ketotif, Stafen) Clematil (Tavegil)
Cromoglycicic acid (Intal, Ifiral, Cromolin) Loratadine (Vero-Loratadine, Claridol, Clarisens, Claritin, Clarifer, Clarotadine, Loradin, Loratin, Lorid,
Loridin, Erolin)
Chloropyramine (Subrestin, Suprastin) Cetirizine (Zyrtec, Citrine)
Corticosteroid Ointment
Betamethasone (Akriderm, Beloderm, Betagents, Betnovayt, Garazon, Diprolen, Kuterit, Triderm, Floisteron,
Celestoderm) Triamcinolone (Azmacourt, Berlicort, Kenacort, Kenalog,
Nazakort, Polkortalon, Triacort, Trikort, Ftorokort)
Sedatives
Bromazepam (Bromazepam, Calmepam, Lexilium, Lexotane,
Norm)
Diazepam (Apaurin, Valium, Dikam, Relanium, Seduxen) Oxazepam (Apo-oxazepam, Nozepam, Tazepam)

Recipes Vangi from pruritus

  1. Boil one kilogram of barley kernels in a large amount of water and bathe the patient in this water.
  2. In this case, you need to expand the pores with the help of bathing and a variety of rubbing.
  3. Aloe and myrrh juice, especially mixed with honey, has a beneficial effect. Drink like tea with honey.
  4. Aloe juice with lentil flour and a small amount  Vinegar is also a good remedy. Celery juice is also often used. Take 1/4 cup after a meal.
  5. Take 50 - 100 g of rhizomes of wheatgrass creeping on a bucket of water and cook in a sealed container. When the water has cooled to 38 ° C, do the bath for 20 minutes. Baths taken daily.
  6. Fill the bath with water, then dilute it with 50 ml of pine extract and 0.5 kg of potato starch or in its place - 1 l thick broth oatmeal. Take a bath at a water temperature of 35 - 37 ° C for 10 minutes.

Itching pregnant

Itching during pregnancy can appear in the first months and at the end of pregnancy, be limited to the external genital area, or spread throughout the body.

Itching in the abdomen and lower back can be caused by the pressure of the uterus on the nerve endings, as well as the stretching of the skin by the growing belly.

Often the itch of pregnant women is painful, causes insomnia, irritability or depressed mood of the pregnant woman. Recognition of this form of toxicosis in pregnant women is not difficult. However, when making a diagnosis, it is necessary to exclude the disease, accompanied by pruritus: diabetes, helminthic invasion, allergic reaction  on medicinal and food substances.

Treatment of itching during pregnancy  comes down to the appointment of agents that regulate the functions of the nervous system, reduce the body's sensitization, and provide a general strengthening effect: diphenhydramine, pipolphen, tavetile, vitamins, ultraviolet radiation.

Itching can occur in any person under the influence of various factors, such as allergies, inflammation, infection, hormonal imbalances or diseases of the internal organs. Folk remedies for getting rid of it have found wide application, but they cannot fully replace traditional treatment.

There are many ways to help get rid of the discomfort associated with pruritus. These include folk remedies, which are based on the use of gifts of nature and other useful components. However, we must remember that treatment should be directed to the root cause of itching, and many folk remedies do not possess such properties.

Healing solutions

A good and effective way to soothe the itching of the skin is a series of infusion. Two spoons of grass will require half a liter of boiling water. You should give the solution time to stand, then moisten a tampon in it and wipe the itchy skin.

Relieve the condition of the skin and produce a cooling menthol effect on it oregano. A tablespoon of the plant is taken per liter of boiling water. When the solution becomes warm, it is filtered and used to treat the skin. For greater effect on the skin are applied compresses containing this solution.

For the preparation of compresses is also used chopped burdock root. It is necessary to take it in the amount of two spoons and, pour water (500 ml), cook for half an hour. Compress can be applied at night.

Good help in the fight against itching alcohol tinctures with the addition of various herbs. For example, you can take one part lemon balm, 5 parts alcohol and insist. Apply the solution for wiping the skin can be after 2 weeks.

On alcohol, you can insist nettle. In this case, 1 part of the leaves of a plant should be poured with 10 parts of alcohol. Infusion time is also 2 weeks.

Some plants are used both for external treatment and for ingestion. An example is lemon balm. For rubbing the skin used lemon balm (10 grams), infused with vodka (50 ml). Insist week.

Itching caused by mosquito bites, passes after wiping skin problem areas with a solution of very strong tea. The tea contains tannin, which relieves irritation and inflammation of the skin.


With bites, a very thick solution-gruel of oatmeal soaked in water also helps a lot. The tool is applied to the affected areas.

Irritated skin is well soothed baths with the addition of decoctions useful plants. For example, in water you can add a rich decoction of barley, pine shoots or chamomile flowers.

It is also useful to apply when bathing juniper extract. The plant has an anti-inflammatory, soothing effect on the skin. In the bath, you should add 4 tablespoons of the extract in liquid form or 2 tablets of dry extract.

Effective oils

One of these oils is almond. Sensitive itchy skin softens under its influence, dry - gets the missing nutrition, affected - is restored. To ensure the desired effect, it is necessary to apply oil to the sites of itching daily.

Vegetable oil becomes good remedy  against itching, if you enrich it with certain components. Thus, several tomatoes fried in vegetable oil will give him their healing properties. This oil should be allowed to settle, and then apply the agent to lubricate the affected areas.


There is another recipe using vegetable oil. To do this, boil 1 cup of this product, then drop 6 finely chopped not very large onions into it. When the onions turn dark, strain the oil. Add to it a prepared grated wax in the amount of a teaspoon. Wait for it to boil again. Reduce heat, boil for another 5 minutes and strain again. Oil stored in the refrigerator and in case of itching to wipe their skin.

Ointment, relieving itching

Effective with itching such a recipe. Take lard, sulfur and grated household soap on a tablespoon, and birch tar - a teaspoon. Stir the ingredients until smooth. After a week of applying this ointment, the skin condition will noticeably improve.

Spoon walnut, ground and fried, grind with raw yolk. Add a spoon to grow. oils. Heat ointment (do not boil), strain. Lubricate irritated areas.

Another ointment with the use of eggs. In this recipe, they take it whole and beat it together with vinegar and water taken in a tablespoon. Cover oiled skin for a while with a cloth.


Quickly relieves itching and nourishes the skin with an ointment containing a mixture of such components: baby cream (tube), golden mustache (tablespoon of the juice of its leaves), valerian tincture (teaspoon), olive oil  (tablespoon). By applying the prepared ointment to the skin, you can not only get rid of itching, but also accelerate the healing of scratching.

Gruel from coltsfoot, minced, slightly diluted with fresh milk. Before going to bed, apply the mixture to the affected areas, cover with a film and wrap.

The means taken inside

Dill has antipruritic properties. A spoonful of plant seeds should be placed in a glass. To the brim pour it with boiling water. Mentally filtered and dill drink mentally divided into three parts and drink in parts during the day. On another day, repeat the procedure. It soothes itchy skin.

Itching often cause nettle burns. But this plant at the same time can be used as a remedy for itching. Eating inside nettle infusion for half an hour before breakfast and evening meals, relieve tension and a beneficial effect on the skin. For cooking means you need to fill one-fourth glass of chopped nettle, then topped up with boiling water and let stand. Infection drink half a glass.

When itching skin helps tea, if you add a lemon balm. The drink is obtained not only healing, but also fragrant and tasty. Drink this tea regularly in the morning and evening.


As a means of relieving itching, Veronica is effective. It is useful to use its infusion in the morning, in the evening and in the afternoon. Every time you need to drink a glass in which a spoon of this herb is brewed. Veronica can be mixed with horsetail in equal parts. Infusion of these herbs is especially good for people. It is very important to know that only horsetail is therapeutic. Other species of this plant (meadow, marsh, and horsetail) may be poisonous.

You can make a more complex drink. Its components will be: burdock roots, licorice and valerian, nettle leaves and violet flowers. Everything must be well crushed, then dissolve 2 tbsp. spoons of the resulting composition in boiling water (500 g). Insist 9-10 hours. Take the infusion three times a day under Art. a spoon.

The composition of the therapeutic drink, relieving itchy skin, may include such herbs as: mint, plantain, burdock root, fennel seeds, nettle. Brewing herbs, let the solution infuse. Eat daily, morning and evening for 30 days.

6. A lot necessary vitamins  contains sea buckthorn. Daily consumption of this berry will help get rid of itching. For greater effect, regular intake should last at least a month.

It should be remembered that it only makes sense to fight exclusively against itching. Regular or accompanied by other symptoms of itching should especially alert. Usually, the final victory over the itch of this nature is possible only with simultaneous deliverance from its causes.

Itching Celandine Itch

Celandine in the form of tincture and decoction for external use - effective remedy  against itching and skin rashes. To prepare the broth, you must take a teaspoon of vegetable raw materials (celandine in dried form can be purchased at the pharmacy) and pour a glass of boiling water. Insist for fifteen minutes and strain through cheesecloth. The resulting decoction can wipe the affected skin or make compresses.

Thick infusion celandine used for baths. It is prepared based on the proportion of 10 grams of dry plant per 100 grams of hot water. The mixture is cooled to a temperature of 36-40 degrees and make baths for 10-15 minutes.

Alcohol tincture for wiping is prepared from one part of the crushed plant into five parts of vodka. To use the tincture as a compress soak gauze and impose it on the affected areas for 15-20 minutes. To avoid irritation of the skin, tincture can be diluted with boiled water.

Other folk remedies for itching

    Lemon balm tea for itching.  Melissa tea has a calming effect, relieves irritation of the skin and reduces itching. For its preparation, a tablespoon of melissa herb is brewed with a glass of boiling water and drunk twice a day. Treatment of itching to continue for a month.

    Bath with a succession in the treatment of itching. Baths with a series of help to alleviate allergic manifestations, remove itching and speed up the recovery of the skin after rashes. Two tablespoons of vegetable raw materials take half a cup of hot water, insist fifteen minutes, cool and wipe the skin with a decoction using a cotton swab.

    Treatment of itching alcohol tincture  calendula  Calendula tincture is used to treat skin diseases, prevents bacterial infections that may occur when combing, reduces itching and helps to restore the skin. It can be purchased at a pharmacy or prepared by yourself, for which 10 g of crushed plant materials are poured with 70% alcohol, insisting for two weeks. The resulting mixture is filtered through gauze and wipe the affected skin. If you experience a burning sensation and pain, tincture is recommended to dilute with water.

    Propolis for itching.Propolis is a substance that is used by bees to protect and strengthen cells, it has a resinous consistency and has powerful anti-bacterial properties. traditional medicine  Propolis is used to treat skin diseases, burns, ulcers, eczema and rashes. The dressing with propolis ointment relieves itching and irritation 10 minutes after application. For external use, propolis tincture of 10% is also suitable, it smears the affected areas to eliminate itching and soften the skin.

List of drugs for pruritus

Antihistamines - which one to choose?

Medications for the treatment of itching and allergic rashes are classified into three main groups:

    Antihistamines;

    Glucocorticoids;

    Mast cell membrane stabilizers.

The most popular and extensive group of remedies is antihistamine preparations that block histamine receptors and prevent the development of an allergic reaction. Thus, itching, swelling and redness after taking this drug a few hours later, the rash becomes less noticeable. Antihistamines have relatively few contraindications, so you can buy them at any pharmacy without a prescription.

A noticeable side effect after taking antihistamines is drowsiness, but its severity depends on the type of drug. Rare side effects - nausea, dizziness, headache.

Antihistamines are divided into three groups:

    First generation antihistamines - drugs that quickly and effectively relieve an allergic reaction, have a sedative effect. They are taken several times a day, because the effect of the application decreases rapidly. There are contraindications for drivers and people who work in conditions of increased risk of injury, since drowsiness is often observed after taking this type of medication. This side effect may be helpful if the patient’s allergic reactions are accompanied by nervousness and sleep disturbances.

    Second generation antihistamines  they do not give an immediate effect, like first-generation drugs, but their effect lasts for a day, so there is no need to take them 2-3 times a day. Sedation is less pronounced, so after they are taken a person can work normally. Allergic reaction begins to subside within an hour after applying the medication.

    Third generation antihistamines  - drugs with minimal sedative effect, drowsiness in patients after taking it appears extremely rare.

Comparative characteristics of antihistamine drugs:

Name

Main characteristics and features of the application

Contraindications

Preparations of the first generation:

Suprastin

Effectively removes an allergic reaction 30 minutes after application, the effect lasts from 3 to 5 hours. Appointed to adults and children from 1 month in case of skin allergic reactions to animal bites and with atopic dermatitis.

Do not use in pregnant women during lactation, as well as in patients with an attack of bronchial asthma.

Quickly and effectively relieves itching, while the side effects in the form of drowsiness are less pronounced than in Suprastin. Validity after a single dose - 12 hours, allowed for use by children from 6 years.

Diseases of the respiratory system, lower respiratory tract, the period of pregnancy and feeding.

Diazolin

Allowed for use at any age, antiallergic properties are mild. Not addictive, so it can be used for a long time.

The drug is contraindicated for pregnant and lactating mothers, as well as patients with epilepsy, digestive disorders ( acute stage  peptic ulcer disease), prostate adenoma, glaucoma and arrhythmia.

Second generation drugs:

Claritin, Claridol, LoraGexal (loratadine-based drugs)

The first results are felt within an hour after ingestion, and the maximum effect appears after 10 hours. The drug is drunk once a day. The likelihood of side effects is minimal.

Not prescribed to children under three years of age, nursing mothers. Women during pregnancy use with caution and only as prescribed by a doctor. Contraindications for patients with intolerance to lactose, fructose or other components of the drug.

Zyrtec, Cetrin, Zodak (ceterisin-based preparations)

Suction takes place in digestive tract, the effect is noticeable after 20 minutes. Not addictive, so they can be taken by long courses. The effect of the drug significantly 2-3 days from the last dose.

Do not designate young children under 6 years of age, women during lactation and patients with renal insufficiency. Older patients increase the risk of edema after the use of the drug.

Third generation drugs:

Prescribed for the treatment of chronic skin rashes, urticaria. The drug has a prolonged effect from 24 to 48 hours, does not affect the ability to concentrate, active attention.

Contraindicated in pregnant and lactating mothers, as well as children under 12 years of age and patients with renal insufficiency.

Prescribed for chronic dermatosis, which is accompanied by itching. The drug has a prolonged effect and does not cause drowsiness.

Violations of the kidneys or liver, cardiac abnormalities, the period of pregnancy and lactation, age under 12 years.


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Ketotifen - a cure for chronic itching

Mast Cell Membrane Blockers - Another Group medicineswhich are used in the treatment of chronic itching. The mechanism of their impact is also to prevent an allergic reaction. So, when an allergen enters the body, it begins to produce immunoglobulins, which, when in contact with cells immune system (mast cells) cause the release of histamines. Histamines are responsible for the further course of the allergic reaction with all its characteristic manifestations - redness of the skin, itching, swelling.

Ketotifen disrupts the interaction of immunoglobulins and mast cells, thus blocking the release of histamine and the subsequent allergic reaction. The drugs of this group do not act immediately, and therefore are not suitable for the relief of acute allergic attacks. The first effects appear after a week of continuous intake, the maximum effect can be observed after 1-2 months.

Ketotifen is prescribed for chronic allergic rashes, such as eczema, urticaria, or atopic dermatitis. It can not be used by women during pregnancy, feeding, as well as young children up to three years. Of the possible side effects - drowsiness, nervousness and irritability, dry mouth and increased appetite, most of them disappear after the first week of administration.

Glucocorticoids (hormones)

This is the most powerful group of drugs aimed at combating allergic rashes and itching. Glucocorticoids affect all types of cells responsible for the allergic reaction — mast cells, eosinophils, and leukocytes. However, due to the large number of side effects, glucocorticoids are prescribed only in the most severe cases. Among the negative manifestations after taking these drugs is a violation of digestion, blood pressureheadaches, and these are far from the most dangerous of all the possible side effects.

Glucocorticoids are prescribed to patients who have tried ketotifen and antihistamine drugsbut did not get the result. It is prescribed in cases where allergic rashes occupy a large area of ​​the skin, causing serious damage to it and painful sensations. Hormonal drugs - prednisone, dexametozon - take no longer than 10 days only as prescribed by a doctor.

Why did an allergist prescribe antibiotics?

Antibiotics do not prevent allergic reactions and do not contribute to the treatment of itching, but the doctor may prescribe in the event of infection. A pustular infection is often accompanied by an allergic rash, the patient himself puts it during scratching of itchy skin.

A doctor can prescribe antibiotics only after special tests. A scraping is taken from the skin, the crop is made in order to determine the sensitivity of this microorganism to antibiotics. Most often, antibiotics are prescribed in this case. wide spectrum  course actions up to 10 days. The drugs of this group are penicillin, cephalosporins, macrolides.


 


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WBC - what is it in the blood?

WBC - what is it in the blood?

   WBC in the analysis of blood is leukocytes or white blood cells. By their number, the specialist determines the general condition of a person and the presence in his ...

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