the main - Infectious diseases
Effective antifungal drugs. Antifungal preparations of a wide range of action in tablets. Names, price antifungal inside

All patients with dermatomycosis tend to choose local, local treatment of affected skin. In some cases, such tactics are really successful. But often after local treatment, mycosis returns and with each recurrence get rid of it becomes more difficult. In this case, treatment with oral systemic drugs is applied.

How preparations work

Antifungal drugs A wide range of action in tablets is available on the basis of synthetic antimicotics. Their action is based on the destruction of the fungus membrane, increasing its permeability, reducing the ability to reproduce the colony.

Some fungi faster than others produce resistance to the action of certain antimicotors. Therefore, unfinished treatment can end that the next time you will have to select the drug with another active ingredient.

Popularity and need for antimycotics is now growing faster, because more and more often patients prefer their home self-medication, independently prescribe themselves antibiotics, they are incorrectly taken and, as a result, oppress their own microflora of the body.

Another reason for the popularity of antimicotics is the cauldronous decrease in immunity against the background of seasonal respiratory infectious diseases, improper lifestyles, chronic diseases.

Consider which antifungal pills of a wide range of action are prescribed today most often, their action and contraindications.

Polyena

Polyens are the class of preparations of the widest range of action among all antimicotics. Popular drugs from this group are Nystatin, Lev Room, Natamicin. They show their activity against Candad, Trichomonad, other simplest.

Polyens resistance are dermatomycetes, pseudo-gallery, because the polyenes are used in the MICOs of the gastrointestinal tract, mucous membranes, leather.

Nystatin

Highly active drug in the fungi of the Candida family. It is not absorbed in the gastrointestinal tract, but in the last period other drugs came to the replacement, although in their absence it is also appointed.

Indications for use are candidiasis of the skin, mucous membranes oral cavity and pharynx, intestinal tract, stomach. In addition, prescribed under therapy of candidiasis after prolonged treatment with antibiotics based on penicillin and tetracycline. It is assigned to some patients after surgery on the gastrointestinal bodies to prevent the development of fungus.

Contraindication to use is only an individual allergic response to the drug. Among the side effects are nauseous, urge to vomiting, abdominal pain, diarrhea, feverish condition.

Lev Room

Exhibits the greatest activity against Candida Albikanis, is also used in relation to the simplest organisms - Leinsmania, Amoeba, Trichomonad. It is also used in the treatment of prostate adenoma - with the use of Lev Rooms, decrease in the size of the adenoma is noted.

Indication to the application are candidozes of the skin, rotogling, intestines, carriage of the fungus Candida, mygoses of the gastrointestinal tract.

Contraindicated to use in case of insufficiency of kidney or liver function, with acute intestinal pathologies, nevikaznaya nature, during ulcers, pancreatitis, pregnancy. During breastfeeding, it is assigned only by decision of the attending physician and with careful observation of the patient.

Pimafucin

Anti-Hikistic Nature Antibiotic, which has a pronounced fungicidal effect. Pimafucin sensitivity show pathogenic yeast fungi, mold, including:

  • Candida;
  • Penicillium;
  • Aspergillus;
  • Fusarium.

Pimafucin in the form of tablets begins to dissolve only in the intestine, therefore practically does not affect other organism systems. Indications for use are thrush, atrophic candidiasis, intestinal micaose, carriage after long-term treatment with corticosteroids, cytostatics, antibiotics. Not prohibited during pregnancy.

Among the contraindications only individual intolerance. Side reactions include nausea, diarrhea, vomiting, which usually pass in a few days and do not require the abolition of the drug.

Azole

Azoles include synthetic antimicotics, and this group is considered the most effective. It is posed by ketoconazole, itraconazole, fluconazole. The first one has already lost its popularity due to increased toxicity, but its analogues continue to be applied in safer forms.

Ketokonazole.

The drug is based on a valid substance with a similar name. There is a therapeutic effect in relation to yeast mushrooms, higher and dimorphic, dermatophitals.

Prescribe at infectious diseases Skin, hair, mucous membranes. Ketoconazole is prescribed only in the case of large areas of damage to fungus. Effective with chronic candidides, dermatophys, dedication, folliculite.

Among the contraindications there are any diseases of the kidneys, liver, the period of nourishing the child and breastfeeding, childhood Up to three years, treatment with hepatotoxic drugs, as well as during the menopacteric period.

Side effects appear in the form owl syndrome In the abdomen, nausea, bad appetite, urges to vomiting. There is a drowsiness, dizziness, anemia, leukopenia, impotence, dysmenorrhea, urticaria, photodermatitis.

Iratenazole.

Analogues of the drug are Itrazol, manungal, mannit, Irunun. Tablets show efficiency with respect to yeast fungi, dermatophytes, mold. The first therapeutic effect can be estimated only a month after the start of treatment.

Indications for use is vulvocandidosis, keratomicosis, dermatomycosis, onychomicosis, aspergillosis, cryptococcosis, multicolored deprived, micaosis of the microwver. Also prescribed in disposant, blastomycosis, hystaplasmosis and other types of fungal lesions.

Contraindications serve high individual sensitivity, period of pregnancy and lactation, deficiency of kidney and liver function, deviations in work humorcraft, severe pathology of lungs and bronchi.

Among the adverse reactions, leukopenia, hypokalemia, thrombocytopenia, anaphylactic nature reaction, swelling, headaches, neuropathy, dizziness, vomiting, constipation, ripping in ears, lack of visual concentration, hepatitis. Erythema, photodermatitis, myalgia, urticaria, erectile dysfunction, amenorrhea, arthlgia are also marked.

Fluconazole.

Popular analogues are Diflucan, Mikomax, Flucostat. Violate the growth of fungal colonies, reduce their ability to reproduce.

Indications:

  • System Candidiasis, affecting the organs of the respiratory system, peritoneum, eyes, reproductive system.
  • The lesions of cryptococci - infectious infection of the skin, blood, lungs, meningitis. Candidiasis of mucous membranes, genitals, as well as as the prevention of mikosa at cancer.
  • With diseases of the fungus of the skin of the foot, nails, with a bubbing lisp.

Among the side effects are marked typical phenomena - diarrhea, nausea, abdominal pain, dizziness, leukopenia, erythema, urticaria. Such preparations are accepted only during food, and drinking with plenty of water.

Allylamans

This group of drugs is most often used in the treatment of dermatomycosis of different etiology and onychomikosis at any stage. Analogs serve Bramzyl, lamizil, terbinox, terbinafin.

Allilalamans show an extensive effect in relation to most fungal hair diseases, nails, skin, in small concentrations are capable of fighting with dimorphic and mold fungi.

Indications for use are micoses on the skin of the head, onychomicosis, fungal lesions of the skin of the foot, the legs, elbow, neck. With a multi-colored delay, practically does not show activity orally.

Among the adverse reactions is a lupus, headache, distortion of taste, dyspepsia, nausea, poor appetite, diarrhea, myalgia, rash, reminiscent of psoriasis. It is prohibited for the use of patients with severe insufficiency of liver and kidney function, pregnant and nursing mothers.

Take orally regardless of food intakes, watered with water. It is categorically contraindicated by the use of alcoholic beverages during therapy with such drugs.

According to a valid chemical group, pharmacological activity in the classification of antifungal drugs, polyenov and non-polyesic antibiotics, azols, allylamine groups, pyrimidines, echinochalandines are isolated.

They have a systemic effect and are often prescribed in the treatment of mycoses Amphotericin preparations in, griseofullvin, micaider. Under dermatomycosis, antifungal antibiotics of griseofullvin, amphogluchene, nystatin are used.

They are increasingly replaced with antifungal drugs lamizil, neungal. In the treatment of candidiasis, preference is given by antimicotics fluconazole, ketoconazole, left-choice, nastatin, miconazole.

Against dermatophytes are used oxyconazole, griseofullvin, tolotclat, tollfathat. Naphtiffin, Natamicin, Amorolfin, Terbinafin, Batrafen, Amphotericin V.

In the modern classification of antifungal drugs, polyenov and unpassed antibiotics are distinguished.

Polician antibiotics

Polician antifungal antibiotics are used for heavy forms of mycoses, in patients with weakened immunity.

The antifungal antibiotic natamicin belongs to the group of macrolides, is distinguished by a wide range of action, the greatest activity exhibits with respect to yeast-like fungi. The fungicidal action of natamycin is manifested in the destruction of mushroom membranes, which causes their death.

Antifungal Candles of a wide range of Natimcin, PyPhamucin, Primafungin, Natamycin ecoofucin as an active substance are used in the treatment of thrush, skin candidiasis.

Pyphamucin is active in relation to mold mushrooms Aspergillus, penicillins, yeast-like Candida, Cephalosporins, Fusarium.

Pyphamucin preparation is produced in the form of tablets, cream, vaginal candle, the remedy refers to antifungal drugs permitted during pregnancy and lactation.

Natamicin is not effective against dermatophists, pseudoallecery.

Amphotericin in prescribed during dermatomicosis, candidiasis internal organs, mold, deep midcosah. The drug is produced in the form of ointments, injection solutions. Amphotericin B is an active in amphogluchene, Funongzone.

Antiform antifungal drugs, Lev Rooms show activity against mushrooms Candidas, are used in complex therapy with prolonged treatment with penicillin, tetracycline antibiotics.

The antifungal antibiotic micokeptin according to the spectrum of action is similar to amphotericin B, prescribed with molding methods, candidias, deep mikosah.

Mycoider toxic, in pills is not prescribed during pregnancy and children up to 9 years.

Unpassed antibiotics

Griefullvin - antifungal antibiotic produced by Penicillium Nigricans. The greatest efficacy of the drug is achieved when taking inside.

Griece Fullwine suppresses the growth of dermatomycete mushrooms, is one of the main drugs in the treatment of tricochy, the microsporium of the scalp, Favus, the nail fungus.

Grieceofullvin contain antifungal agents Grickin, Griffin, Griffulvin, Fulzin, Fulwin, Grizefulin, Lamoril, Sportatin.

Griezofulvin is effective when taking inside, in the form of tablets, this antifungal agent is prescribed at a ring-free license.

The antifungal agent of griseofullvin in the form of a suspension is used to treat children under 3 years. Teenagers and adults prescribe a drug in tablets, the daily dose is calculated at the calculation of the patient's weight.

Grieceofulvin is not used in candidates, is not prescribed during pregnancy, lactation. The drug has a teratogenic effect, the danger to the fetus is maintained during the year after treatment with griseofullvin.

Synthetic antimicotics

Modern antifungal agents belong to synthetic drugs, have a wide range of action, used at local and systemic treatment of mycoses. The group of synthetic antimicotics includes azols, allylamines, pyrimidines.

Azole

Antifungal drugs from this group exhibit a fungustic - the suppression of the reproduction of fungus, and a fungicidal action.

Fungicidal properties are expressed in the destruction of mushroom cells, the effect is achieved only at high concentrations of antimicotics. The Azol group includes:

  • ketoconazole, bifonazole, clotrimazole, econazole, miconazole, oxyconazole, butoconazole, isokonazole, sector, fenticonazole - imidazole;
  • vorikonazole, Fluconazole, Iratenazole - Triazoles.

Among the triazoles, voriconazole and itraconazole are the highest activity.

Antifungal agents containing voriconazole have a wide range of action, effective in the treatment of aspergillosis, candidiasis, multi-colored losing, subcutaneous and deep mycoses.

Vorikonazole is part of the pills and powder Vifend, voriconazole, Vicand, Biflurine tablets.

Antifungal drugs of this group are used in the treatment of severe fungal infections, long-term intake of antibiotics, in case of danger of fungal infection after organ transplantation.

Antimicotics containing itraconazole possess the almost as wide range of activity as preparations with voriconazole.

Applied in the form of capsules for intakes in the system treatment of mold, candidal micaoses of the skin, nail fungus, vulvogenic candidiasis, deep mycoses.

Itraconazole is contained in the preparations of itrazol, itrazonazole, manungal, rumicosis, manholes, hatters, Canditral, Teknazol, Arenong, Irunun.

Antifungal drugs based on fluconazole are effective in the treatment of candidsesms, dermafilation, deep mycoses. But not active against mold fungi, a number of fungi candidates.

As an active compound, fluconazole contains the microsist, diphlasone, mycoflucan, combined means of the saffocide, dieflux, flukostat, funcon, antifungal gel with fluxe.

The imidazol group includes both antifungal drugs with well-known properties that have long been used in medical practice and new drugs.

New synthetic imidazoles, effective against candidate mushrooms, applies to the antifungal drug of a wide range of Fenticonazole.

Produced in the form of capsules for intake, vaginal capsules and friction cream.

The drug is treated with genital candidiasis in men and women, the cream has antibacterial activity, used with vaginal trichomoniasis.

The third-generation imidazole is ketoconazole in efficiency and the spectrum of action close to itraconazole, but is not active to the mold mushrooms Aspergillas, as well as some strains of Candida.

Ketoconazole contain antifungal ointment microsl, dug, semozol, micketers, cream and shampoo noodles, shampoos for people keto plus, Mikanisal.

Antifungal medications with bifonazole as a active substance are used primarily for external treatment, there are fungicidal and fungistatic activity.

Bifonazole penetrates deep into the skin, remains for a long time in tissues in the therapeutic concentration, produced in the form of creams, lotions, Kaporno gel, bifon, microspore, biphosin, bifonazole powder.

The current Clotrimazole active substance is part of antifungal agents. Candad, Canison, Amiklon, Cauren, Imidil, Lotrimine, Candyzole, Kllomegl.

It is widely used for the treatment of micaosis of the skin Antifungal tool Candad-B, with a thrush in men - the ointment of Clotrimazole.

Preparations containing antifungal agent Sertaconazole are distinguished by a wide range of actions, it is used externally for the treatment of mycoses of the skin stop, head, beard in men, torso, skin folds.

Sertaconazole contains cream Zalayan, cream and solution of sourmolomol, vaginal suppositories with lidocaine optipal.

Comparative features

In the group of Azols, ketoconazole has the greatest hepatotoxicity, the drug is used mainly for local treatment.

A less toxic drug from Azol is considered to be fluconazole, however, it is capable of calling side effects:

  • allergic reactions;
  • headache, sleep disorders, convulsions, impairment;
  • nausea, vomiting, stool disorders.

Fluconazole is allowed from antifungal preparations of the Azol Group during pregnancy.

It is prescribed in the methods of different localization, including in the prevention of fungal infection during radiation therapy or treatment with antibiotics.

Allylamans

Representatives of Allylamines - synthetic preparations Terbinefin, naphthiff. In the classification of antifungal drugs, terbinafin as an active component is included in the composition of the antimicotics of a new generation.

This group includes antifungal pills, creams, ointments, sprays for leather lamizil, exifun, terbinafin, fungoterbin, Lamizil Dermagel, Binafin, Atiphin, Mykonorm, Gel Mikoperon.

The terbinafin has a fungistatic and fungicidal effect, is a drug selection in the treatment of dermatophytium, candidiasis, chromomicosis, onychomycosis, deep mycoses.

Preparations with terbinefin are active against all known fungal diseases, as well as against leishmaniosis and tripanosomosis caused by the simplest.

Antifungal drugs with terbinafin are used to intake in tablets in tablets with smooth skin of the body, legs, heads, nails of stop, brushes.

Medicines with an active substance of terbinefin are prescribed with systemic treatment of extensive foci of microsporia, tricochy, candidiasis, chisden depriving, chromomicosis.

Treatment of terbinafin from nail fungus gives a positive result in 93% of cases.

Antifungal drugs containing an active ingredient naphtyphin include cream and exoderyl solution. Medicines are used to treat skin, nails, applied locally 1 time per day.

Echinocandines

The group of new antifungal drugs Echinocandins includes Anidulaafungin, Kaspofungn, Mikafungin. Echinocandine antifungal drugs are not allowed for the treatment of children under 18, during pregnancy, lactation due to lack of data.

Other groups of antimicotics

Preparations with amorolphine Ophlomil varnish, Loceteril applied from mycoses of nails, candid by nail and skin.

The connection is included in varnishes, creams of bat-path, phonographic, vaginal cream and candles Daphnegin. Exterior tools are effective in onchomicosis, candidides of the skin, dermatophytium.

Flucitozin

The drug of this group Ancotil is used to treat aspergilleesis, unaccounted methods, cryptococcosis, candidoid septicemia.

Chlorinitrophenol

The nitrophina solution is used externally for the treatment of mikosa stop, groin epidermofitilation, candidiasis, nail fungus, dermatophytium.

Nirtophungin inhibits the growth of colonies of microorganisms, kills the mushroom cells, is used in the treatment of mixed infections in the case of bacterial infection. Contraindicated in pregnancy and children under 2 years old.

Exterior means

Modern synthetic antifungal drugs in tablets, solutions for infusion and outdoor use, ointments, creams, varnish for local treatment have a wide range of actions.

In the treatment of the nail fungus, the foot to ensure the access of the antifungal agent to the lesion focus, pre-delete the detachment of the horny surface layer of the skin.

It includes naphthalan, sulfur, ichthyol, salicylic acid in a mixture with dairy, tar in the mixture of sulfur.

From the fungus of the skin, nails are treated with antifungal ointments, grassortort creams, lotriders, trieders, Sikortin Plus, Sinalar K, Sanguiritrine.

A deep action on fabrics are antifungal varnishes. Varnish is a colleague in which the medicine from fungus is introduced. When applied to the nails, the skin, a thin film that has a healing effect is formed on the surface. Nail fungus is treated with Loceryl varnishes, battroof.

Not lost values \u200b\u200bin the treatment of ointment mushrooms containing tar, sulfur, edicilene acid, alcohol solution of iodine, aniline dyes.

For the treatment of scalp skin, antifungal shampoos nipped, microsyl, cinovit, Sebiprox, Mikanisal.

For the treatment of micaosis of the skin of the face, skin folds, the scalp, beard, smooth skin of the torso use antifungal ointment nastatin, amiclon, lamisyl.

Antifungal ointments tend to have restrictions on age and a large list of contraindications are not allowed during pregnancy during lactation.

Self-treatment with antimicotics is dangerous, the uncontrolled application of antifungal agents can cause allergies, dermatitis, disrupt the work of the liver.

Systemic therapy with antifungal drugs causes fewer side effects with simultaneous reception of vitamins, hepatoprotectors.

Antifungal preparations for children

Gentle skin of newborns, infants, kids up to 3 years old are more susceptible to fungal diseases than the skin of adults. Tallery on the skin serve as an entrance gate of the yeast-like mushroom Candida.

For the treatment of children permitted antifungal ointment Candide-B, with damage to mucous membranes - Pyphamucin drops.

With diaper dermatitis, nastatin ointment is used, rewrings are produced with a nastato. Using powders, care caution: the child should not inhale the powder.

Kids up to a year and older are treated from skin candidiasis with Cream Clotrimazole or its analogues: Clotrimazole-acry, candiben, imidyl, candy.

Antifungal ointments with clotrimazoles are used in adults for the treatment of urogenital infections, eliminating itching in intimate zone, Symptoms of infection.

In children, over 3-5 years old, skin diseases of the scalp - microsporia, tricochy, known as a ringing deprived, as well as epidermofitilation stops, arise.

Antifungal drugs for the body, legs, skin with clotrimazoles are effective for all types of skin microse, they differ in the available price, allowed to children.

Many plants possess antifungal properties.

Anti-Green Activity Exhibits Black Currant, Dill, Sage, Black Tea, Ginger, peppermint, lemon. In the absence of allergies, the child is weak rags of plants skin folds, Tallery on the skin.

Preparations in the treatment of mycoses

Fungal diseases are treated with complex, several drugs are prescribed to expand the spectrum of action, various forms of drugs are used - ointments, creams, tablets, solutions.

Systemic treatment of deep mycoses

  • Antifungal antibiotics amphotericin in, micaider.
  • Antifungal agents based on micronazole, ketoconazole, itraconazole, flukonazole.

Dermatomicosis

  • Antifungal antibiotic griseofullvin.
  • Antimicotics with terbinafin, chloronitrophenol (nitropungin), iodine preparations.

Candidation

  • Antifungal antibiotics Levuary, Nystatin, Amphotericin V.
  • Antifungal agents with miconazole, clotrimazole, chloride decal.

For more information, see "".

Combined treatment With the use of multiple drugs, it is necessary for the most complete coverage of all possible macosuers.

Thus, new antifungal drugs from the Echinocandine group are not active against cryptococci. The effect of echinocandines is enhanced by the appointment of amphotericin in the overwhelming cryptococci growth.

Positive results of treatment are noted when prescribing complex therapy in patients with immunodeficiency states. The combination of antimicotics is selected depending on the type of mushrooms, aggressiveness, the state of the patient.

Mycosis or fungal lesion of nail plates is one of the most ancient diseases. It is impossible to develop immunity to mycosis. And the only effective means of prophylaxis is the observance of personal hygiene.

In the last half, there is a slight decrease in the number of fungal diseases. However, mycosis continues to maintain leading positions among all skin problems. To date, more than 400 strains of fungus attacking the human body are known. All these strains are distinguished by high contagiousness and the ability to maintain their pathogenic properties for a long time. The best habitat for fungus is warm and wet surfaces. Therefore, fans of pools, saunas and baths are under the blow.

A feature of mycoses is their stability and immunity to therapeutic measures. In most cases, the patient who negligently refers to his own health is responsible for unsuccessful treatment and does not fulfill all the instructions of the Doctor regarding treatment or the decision on the cessation of treatment after the first improvements.

All this leads to the development of complicated MICOS, sustainable to most drugs.

Early self-diagnostics of pathogenic fungi makes it possible to quickly and easier to defeat the disease. The main signs of the Mikosa, which can be found independently, are:

  • Outlet of the skin stop;
  • Cracks on the heels;
  • Burning and itching;
  • Redness of the epithelium;
  • Scalyness and skin detachment;
  • Change coloring nail plate (formation of yellowish spots or strips);
  • Thickening of the nail plate;
  • Delamination of the nail plate, changing the edge of the nail, its partial destruction.

Medical treatment of fungus

Preparations used for the treatment of mikosa are called antimicotics. They include a wide range of diverse medicines effective in combating fungus. Some of them are obtained from natural compounds, others exclusively in the chemical laboratory. All means for treating fungus are divided into several categories or groups depending on:

  • Pharmacological composition;
  • Pharmacodynamics (characteristic effects on different strains of mycoses).

All anti-grab drugs have a number of contraindications and adverse reactions, so the purpose and duration of the reception is determined exclusively by a dermatologist!

When prescribing antifungal drugs for intake, it is important to clearly observe not only the duration of the reception, but also the frequency (take the drug at the same time), if possible, avoiding the passage of the drug.

How do pills from fungi

The effect of antifungal preparations of a wide range of action in tablets is based on their fungicidal properties - the liquidation of the spore of the fungus and the obstacle to the reproduction of pathogenic microflora.

The antimicose drug when taking inside quickly falls into the blood and begins the attack on the spores of the fungus. The active ingredient is in active condition for a long time, and then derived by naturally. Different groups Drugs from fungus differ in pharmacological action. This is due to the components included in their composition.


Typology of effective tools from fungus

All mycoses can be divided into two groups:

  1. Outdoor mycoses attack nail plates, epithelium and hair cover;
  2. Hidden or internal fungal pathologies affect the internal organs of man.

In the therapy of fungal diseases are used:

  • Local antibiotic against fungus;
  • Capsules from the fungus of a wide range of action.

By writing down the recipe for one or another drug, the dermatologist takes into account the clinical studies and prescribes an inexpensive remedy for fungus effective for the treatment of a strain of Mikosa.

Group of effective antifungal drugs

Depending on the incoming composition of the atymicotics of substances, their pharmacological effects are isolated by polyenes, azols, allylamines, pyramidines and echinocandines. Consider a list of the most effective means of fungus presented in domestic pharmacies.

The first group of antimicotics - Polyen

Antifungal tablets of this group act on a large number of pathogenic microflora.

In the Antimicotics Polyen Group include:

  • Nystatin;
  • Lev Room;
  • Amphotericin in;
  • Nitamicine or pimafucin.

With the help of polyenses, struggling with candidides of the mucous genital organs and larynx, epithelium, as well as fungal diseases of the stomach.


The second group of anti-gribery products - Azole

Inexpensive antifungal drugs of synthetic origin.

These include:

  • Ketoconazole;
  • Fluconazole;
  • Itraconazole.

Ketokonazole was one of the first cheap means of combating mikozami. However, due to the large number of complications, it was replaced with itraconazole and is used exclusively for local therapy. Azoles - the best means from the fungus of the epithelium, nail plates, hair and individual strains of deprivation.

Ketokonazole.. The active ingredient included in its composition is imidazoldiocolean. Antibiotic against fungus is effective for therapy:

  • Dermatophytes;
  • Yeast-like mycoses;
  • Higher micoses;
  • Dimorphic mycoses.

In the tablet form ketoconazole you need to drink with such diseases as:

  • Folliculitis;
  • Chronic form of candidiasis;
  • Dermatophyte;
  • Multicolored deprived;
  • Recurrent mixing vaginal.

Ketoconazole - effective tablets From fungus, resistant to other anti-grays. Contraindications are chronic diseases of the internal organs. Possible side manifestations: Allergic rashes, jumps arterial pressure, nausea and disorder of digestion, dizziness and drowsiness.

Iratenazole.. Chemical antimicose tablets have an effect against a large number of strains fungus:

  • Yeast mushrooms;
  • Dermatophytes;
  • Mold mushrooms.

With the help of drugs, it can be defeated:

  • Dermatomycosis;
  • Vaginal and vulvocandidosis;
  • Multicolored deprived;
  • Keratomicosis;
  • Mikoz nail plates;
  • Candidia of mucous oily cavity;
  • Cryptococcosis;
  • Spothost;
  • Blastomycosis;
  • Hystaplasmosis.

It is prohibited to the appointment of itraconazole women who are waiting for a child and mothers who are breastfeeding. Possible side effects: skin rashes, violation of the menstrual cycle in women, problems with vision.

Fluconazole.. The best antifungal drug prevents the growth of mycoses in the body and opposes their replication. Effective in the treatment of such infections:


Not used for nursing mothers, with caution is appointed to women waiting for the birth of a baby and people suffering from heart disease. Possible allergic reactions and digestion problems are associated with individual sensitivity.

A feature of the reception of antimicotics of the azol group is their use along with food and picking up with plenty of water. Incompatible with simultaneous admission of pimoside, terphenenda, asthyisol, quinidine, lovastatin.

Third Group - Alliamides

A group of synthetic means for removing fungus. The effect of allyamides is due to the exposure to dermatomyosis - fungal infections of nail plates, hair cover and epithelium.

Terbinefin.. Used in therapy:

  • Onichomicoses;
  • Hair fungus;
  • Dermatomycosis of the epithelium of the body and stop.

Contraindications are chronic liver diseases and kidney diseases, for women - the period of tooling the child and breastfeeding. Occasionally, allergic reactions in the form of rashes, headaches, disruption of taste receptors, problems with the assimilation of food. The drug is taken regardless of food. Incompatible with alcohol.

Preparation for heavy molds

Griecefullvin. Effective from dermatomycetes. This is due to the natural origin of the antimicotics. This tool is called best medicine From fungus. Griseofullvin therapy is effective even with the most severe forms of fungal diseases. However, it is not justified for the treatment of light micose manifestations. Such strains are susceptible to the Griestuofulvin:

  • EPYDERMOPHYTON;
  • TRICHOPHYTON;
  • MicroSporum;
  • Achorionum.

It is used in the treatment of microspories of epithelium, hair and nails, triphides, epidermofitis, dermatomycosis. It is not appointed for children to two years, patients with oncology, chronic blood and gastrointestinal diseases, during pregnancy and lactation. Possible side effects from digestive and nervous system, as well as allergic manifestations caused by individual sensitivity to the components of the drug. You can take the griestoofulvin during or after meals, for better assimilation, the drug intake is combined with a tablespoon of lean oil.

Preparations for outdoor removal fungus

In the therapy of the Mikosa Stop and Nail Plates, it is first necessary to sick the burdered layer of the epithelium.

Keratolithic ointments, such as naphthalan, ichthyol, salicylic acid have a sprinkling effect.

Antimicotic creams, gels and ointments are used from the epithelial fungus:


A good options for the treatment of onychomicosis is the application of medical varnishes on an affected mushroom plate - Loceryl, barafin. They are able to penetrate deeply in the nail and continue to fight with mycosis, forming a protective film on the nail surface.

Despite the ever-growing standard of living, the fungus is found almost every second inhabitant of the Earth. The treatment of any fungal damage is impossible without the use of medicines, but for successful healing, it is necessary to use only high-quality and effective antifungal drugs, from the list of the best medicines.

Compound of quality and efficiency does not always mean the acquisition of superdowed medicines. There is enough inexpensive drugs Against fungus, which are characterized by high efficiency and rapid effects. In addition, in the treatment of fungus, it is possible to use analogues of expensive drugs that give the same result as the original drug.

Differences and features of antifungal drugs

Preparations against fungus are selected depending on the duration of the proceeding of methods, on the volume of the affected surface, the presence of concomitant diseases, the nature of the manifestation of the fungus.

The form of the release of antifungal agents is diverse - they are produced in the form of tablets, ointments, gels, solutions, candles. A variety of output forms allows to treat not only external forms of mikosa (feet, genitals, nails on legs and hands) and internal manifestations of fungus. Systemic effects have antifungal drugs in tablets, gels, ointments, sprays, creams are used for local treatment.

Modern pharmacology allows you to successfully treat fungal diseases of any nature.

Note! Therapy with one drug Usually does not bring the desired effect, because Often, several types of pathogens are somewhat at once. Therefore, the doctor must appoint a comprehensive treatment of fungus.

A fungal infection is easily adapted in any conditions, quickly developing resistance to various active substances. Therefore, it is not necessary to independently select the drug from fungus, because This can lead to mushrooms and the development of more stable forms.

When antifungal drugs are used:

  • Mycosis;
  • Yeast skin infection;
  • Cryptococcosis;
  • Fungal infections respiratory tract, eye;
  • Vaginal;
  • Parakeoccidoidomycosis;
  • Histoplasmosis;
  • Epidermofilation of the groin area;
  • Yeast skin infection;
  • Candidemia;
  • esophagus and oral cavity;
  • Spothost;
  • The mushroom of the scalp;
  • Diallos;
  • Body skin fungus.

Therapeutic agents against fungus are aimed at the destruction and destruction of causative agents of the disease, and stopping the spread of infection. Some of the drugs successfully defeat dermatophyphibes (mold mushrooms), others are directed to the destruction of direct yeast mushrooms. Therefore, drugs are selected depending on the type of pathogen, which is determined by the doctor after carrying out appropriate analyzes.

Review of drugs against fungus

Preparations from fungus are classified depending on their chemical structure, clinical purpose and spectrum of action. The most common and efficient drug antifungal agents belong to groups of azoles, polyenov and allylamine.

Polyenov Group

Polyens - antifungal preparations of a wide range of action in tablets and ointments, which are most popular in the treatment of mycoses. Most often, they are used for therapy of candidosis of mucous membranes, skin Pokrov, gastrointestinal tract.

List of drugs:

  • Nystatin - produced in the form of ointments and tablets for the treatment of fungus mucous membranes and body skin. Used with candidiasis of skin, intestines, vagina, oral cavity. Practically does not have contraindications, side manifestations are possible in the form of allergic manifestations. The course of treatment lasts from 10 to 14 days (in accordance with the instructions). Price - from 40 rubles.
  • LEVAORIN - used in the candidides of the gastrointestinal tract and leather, has a high activity against Trichomonade, Candida Mushrooms, Leinsmania. It is not allowed to use during pregnancy, under the age of 2 years, during the period of lactation, with hepatic and, with, bowels and stomach ulcers. Price - 100-130 rubles.
  • Pimafucin - has an impact on a huge number of pathogenic fungi affecting the body. It is assigned when candidides of the gastrointestinal tract, vagina, to remove the consequences of antibiotic and corticosteroids. Price - from 250 rubles.

Group of Azol

Azoles are synthetic preparations used with the therapy of mycoses of the scalp, skin, for nails of feet and hands ,. Some drugs in this series are used to treat candidiasis of mucous membranes and thrushs.

List of antifungal drugs:

  • Ketoconazole is a drug against dimorphic and yeast-like mushrooms, folliculites, dermatophytes, seborrheic dermatitis, chronic candidiasis. Frequently used for the skin and treatment of the head fungus if a high degree of lesion and resistance to infection is observed. The drug can cause extensive side effects, caution is appointed to children and elderly patients. Price - from 100 rubles.
  • Myxoral - ointment for the treatment of epidermofitilation, sebuguene, seborrheic dermatitis, dermatomycosis, candidiasis of various types. Antifungal drugs for nails, hands, stop, based on the active substance of ketoconazole, are also produced in the form of shampoos and tablets inside. Price - from 200 rubles.
  • Semozol - preparation in the form of shampoos of ointment used against yeast-like mushrooms, dimorphites, and. Used for the treatment of fungal lesions of stop, nails, scalp, hands. Price - from 130 rubles.
  • Fluconazole - has a wide range of effects in the defeats of Cryptococcus fungi, the cavity of the oral cavity and the pharynx, the respiratory system, the reproductive system organs, nail fungi, lichen. Caution capsules are used during pregnancy, with pathological diseases of the liver and heart. Price - from 20 rubles.

Note! Mazi from fungus can be used as an independent means from Mikosa, if the area of \u200b\u200bthe damage is insignificant and the disease is in the initial stage. In other cases, ointments are used as a comprehensive fungus therapy.

Allylamine Group

Preparations of this series are actively struggling with dermatomicosis - fungal lesions of hair, skin, nails.

The most common means of this group is terbinafin. This is a local application (cream, ointment) used in the treatment of nail and skin fungi, dimorphic and mold pathogenic microorganisms. Assigns with severe fungal lesions of nails, stop, head, torso. Price - from 48 rubles.


The active substance terbinafin destroys the cells of the membrane fungus and provokes the death of the fungal colony. In addition, the substance does not accumulate in the body and is removed entirely through the liver, which allows the use of means based on it for the treatment of mycoses in pregnant women and children.

Inexpensive antifungal analogs

There are a lot of drugs against fungus, but mostly these medicines are analogues of each other. This is because over time, the patented dosage formula becomes available to other pharmaceutical companies, which are based on it generics - identical in composition and the action of medication, which at the same time are not so expensive at the price.

Generics have their own name of the drug, but calculate whose analog they are, it is possible by the active agent drug that is prescribed on the package.

Terbinefin, one of the most effective means against fungus, has the following analogues:

  • Terbizol;
  • Binofine;
  • FungOTerbin;
  • Expin;
  • Lamican.

The active substance Fluconazole is contained in preparations:

  • Fusis;
  • Diflucan;
  • Nofung;
  • Microsist;
  • Mikoflukan.

Ketocanazole has the existing analogues - Fungavis, lowland, microsyl.


The cost of anti-grab drugs is not always associated with quality. Cheap analogues of expensive antimicose drugs, as a rule, are not inferior in efficiency.

The price of drugs against fungi varies from very expensive to completely cheap means with absolutely identical efficacy of drugs. The most inexpensive analogues are found in a series of ketoconazole and fluconazole preparations. The analogues of terbinafin occupy an average position, and the most expensive are drug-based drugs (Itramick, Irunun, ITRAZOL, Canditral).

Antifungal preparations for children

Antifungal drugs for children mainly use local - ointment, creams, sprays, powders for outdoor use, varnishes, drops, shampoos. Local use tools are based on the actions of the active substances of the triazole, allialamina, imidazole.

Local preparations are most effective in the treatment of candidiasis, epidermofitilation and multi-colored deprivation.

When candidalous child prescribe preparations in the form of tablets or plates for resorption. Treatment of fungal infections in organs of vision is based on the use of a suspension with a nastatin. Children are treated with a special varnish, which not only neutralizes the colony of fungi, but also creates a protective film on the nail plate.


The most common topics of local applications are:

  • Mikosan;
  • Nystatin;
  • Amorolfin.

Systemic therapy is carried out only with the occurrence of large foci of lesion and rapid propagation. To systemic drugs include:

  • Fluconazole;
  • Myxptin;
  • Terbinefin.

Independent treatment with antifungal drugs in pediatrics is not allowed, because Medicines have a number of side effects and contraindications. The correct treatment plan can only be a qualified doctor.

Tablets from fungus - the most effective way to combat all kinds of mycoses. In the treatment of fungus it is important to take treatment comprehensively and on the system. In situations where the result from therapy is absent for a long period, it is impossible to change independently when treatment has been treatment.

Comparing treatment with tablets with other ways:

  • The effect of tablet therapy is higher by 80%.
  • A relatively simple treatment process.

Symptoms of fungal diseases and types of infections

There are globally two types of fungal infections. Deep and superficial. Skin deprived, nail fungus belong to the surface form of the disease.

Before making a diagnosis and write down the direction for the pharmacist, the doctor estimates the scale of the problem. This directly affects the future treatment plan fungus.

Onychomicosis / nail fungus

- This is a form of fungus, which in the people called a ringless deprived. Pathways of this disease:

  • mushroom Trichophyton;
  • mushroom Microsporum Canis.

Extremely infectious disease. First of all, affecting people with a weak immunity. Little children, people of old age are in the risk area when contacting the carriers of these mushrooms.

Symptoms:

  • A red spot with clear boundaries appears on pure skin in the place of infection.
  • Light form Item.
  • A slight increase in spot size.
  • The appearance of bubbles along the contour at the initial stage, and through time they disappear.
  • The central part of the stain becomes light pink.
  • The appearance of a light shape of peeling.

Candidiasis / thrush

To the deep form of infection with a fungal disease (mycosis), applies candidiasis. More known as thrush. The causative agent of this disease is the genus genus Candida. The overall decrease in human immunity gives a chance to this yeast-like mushroom to get into the body through the gastrointestinal or penetration through the skin. Internal organs may be infected with this fungus.

Symptoms:

  • Lung pneumonia, bronchitis, sinusitis - cough.
  • Inflammatory processes GCT, esophagus.
  • Men should be attentive to such symptoms as a burning sensation when urinating, various allocations.
  • White cottage-like raids on the shells of mucosa in women.

Attention! After antibiotics, the therapeutic effect is not observed, the symptoms of the disease fungus do not decrease.

Seborrheic dermatitis / Seborrhea / Dandruff

Pityrosporum Ovale fungus pathogen.

Fungi live on the body 90% of all people on Earth. Under favorable conditions, this fungus increases several times in a rather short period of time. This is exactly what leads to violations in the process of exfoliation of dead skin. The growth of new skin is also broken. There are special dandruff shampoos with damage to the fungus of the scalp.

The launched shape of seborrheic dermatitis is treated with a complex.

Symptoms:

  • excessive dry skin of the head;
  • itching in places of damage to fungus;
  • abundance of white scales on the head falling on the shoulders.

What do doctors contact with suspicion of fungal disease?

When symptoms of skin fungus appear for consultation to dermatologists.

Problems nail fungus He examines and solves a mycologist.

Increased dandruff and damage to the fungal diseases of the head of the head - we appeal to a trichologist.

In case of urological problems occurs, you should contact the dermatologist.

Is it possible to cure a fungus with pills?

Tablets against fungus undoubtedly exist, their huge amount. In each individual case, different forms and dosages of the drug are applied.

Important! Starting comprehensive treatment of fungus with tablets and ointments, it should be remembered about contraindications and possible side effects. It is not necessary to independently increase the course of treatment with pills or stop them before the specified period of the duration. Any actions are coordinated with the attending physician.

Receiving assigned tablets must be carried out at the same time. If one reception was missed, you need to drink the next dose as soon as possible, but double the number of filled tablets it is categorically impossible.

The cessation of treatment threatens the probability of re-illness with the new fungus or recurrent of the old disease.

Active substances in drugs treating fungus / myozes are combined into a group called antimicotics.

The list of antifungal drugs consists of tablets and a capsule of a wide range of action, creams, ointments, vaginal pills, candles. In addition, there are natural origin medications that can be used in the treatment of fungus at the initial stages. Or for preventing fungal diseases.

Thanks to the fungicidal actions of the tablets, the destruction of fungal dispute occurs and the conditions are unfavorable for their subsequent reproduction.

Medications Against mycoses, hitting the body, quickly absorbed into the blood and attack the disputes of mushrooms. The active substance of the tablets remains active in the human body and then dismissed naturally.

According to the pharmacological basis, there are:

  • Tablets in which the active substance is ketoconazole (the commercial name of the nipped, microsyl), work on the principle of obstacle the formation of the micaose membrane at the cell level.
  • Itraconazole (commercial name of the Irunun Tablets, Nurson, Omannimine) and terbinafin (commercial name Tablets Eczifin, Exceiver, TEVA, Terbizil, Termicon), work according to the principle - an obstacle to the development of fungal dispute by suspending Ergosterol's production in mushrooms.
  • Flucanazole (commercial name Diflucan tablets) destroys the fungal formations available in the body and do not give a new one.
  • Griezovulfin, these tablets put obstacles to dividing fungi at the cellular level.

What is the most effective pills from fungus?

There is no unambiguous answer to this question, since all pills operate according to a different principle.

Tablets Nystatin

Some of the most inexpensive tablets From the fungus on the body. It has been invented for a long time, but due to a large percentage of complications when taking, over time, it was replaced with better analogues with the active substance by itraconazole. At the moment, ketoconazily containing drugs are applicable only for local processing of the affected area.

Anti-Grybkaya Group of means called Azole Highly Effective launched fungus, from fungus under the mouse. In particular, when treating fungal foci of epithelium, nail plates, hairproof and some forms of skin deprived.

Preparations, the active substance whose ketoconazole work well where resistance to other antimocols has been revealed.

Contraindications include chronic internal organs.

Side effects: allergic rash, lethargy, dizziness, blood pressure drops.

Tablets Fluconazole.


Self best tablets, creams, ointments, sprays from growing fungal dispute. Actively oppose their replication.

Fluconazole is effective and affordable. Perhaps its popularity is related to low cost.

For the treatment of vaginal candidiasis (thrush), one tablet of fluconazole in the dosage of 150 mg is taken. Next, in preventive purposes, the same dose is used, but once a week.

Side effects - Allergies to the active ingredient of the drug, minor changes in the blood, violation of the food digestion process, painfulness In the area of \u200b\u200bthe abdomen.

Attention! Nursing mothers are contraindicated in this drug. With great care, pregnant women are appointed, for example only after 32 weeks of pregnancy in the form of vaginal candles. It is contraindicated to people who have a history of chronic heart disease.

Tablets terbinafin


Tablets from the allyamide group. Synthetic means for removing fungal lesions. The active impact on the leather and nail dermatomymicosis.

Contraindications include pregnancy and period of GW in women, chronic diseases in the field of liver and kidney.

Side effects are expressed in the form of taste changes, poor digestibility of food, headaches. Occasionally allergic rash. Incompatible with the use of alcoholic beverages.

The dosage and duration of the course of treatment with terbinefin is determined from the degree of infection and the neglence of the disease.

Due to the fact that the drug has a large list of side effects, independent appointment of this drug is unacceptable. Treatment should be carried out only under the control of the attending physician.

With a novel dermatomymicosis, the tablets should be taken until the reflection of the healthy nail plate. An analysis is also conducted on a tank of seeding space affected by mushroom disputes.

With any form of triteophoth, the treatment will take from two weeks to a month in a complex with local antifungal drugs.

Tablets Lamizil


One tablet of laminizila from the fungus contains 250 grams of the acting matter of terbinafin. Also, this drug is represented as a spray, gel, cream and liquid for outdoor use.

The preparation of a wide range of action. After the start of treatment with laminizil, inside the skin, on hair and nails, such a concentration of the drug is created, which provides a fungicidal effect.

Tablets lamizil are more effective than the same drug outdoor use, when combating multicolored, deprive.

Only sensitivity to the active substance or its components can be attributed to contraindications.

Tablets Griestuofulvin


The drug is prescribed for the most launched and complex fungal diseases.

For children under two years old, the Tablets of the Griezovulfin are not prescribed.

Oncobole, patients with ulcers, with chronic diseases blood is also not prescribed.

Tablets Iratenazole


Antifungal preparation of a wide range of action. Apply with fungal lesions of the skin, mucous membranes of the oral cavity and eye surfaces.

For breastfeeding, It is necessary to stop the GW process for a while, the drug penetrates into milk.

Possible side effects: constipation, vomiting, nausea.

The modern market was flooded with goods for the treatment of fungal diseases produced in India and China.

Well, if after their application there will be no result. But it may be harm. So, before engaged in self-treatment with drugs of dubious origin, think carefully and consult a doctor.

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